Breast cancer stands as the most prevalent and heterogeneous malignancy affecting
women globally, posing a substantial health concern. Enhanced comprehension of tumor …

Cancer is one of the leading causes of death worldwide. The tumour extracellular matrix
(ECM) has unique features in terms of composition and mechanical properties, resulting in a …

Tumor metastasis is a leading cause of mortality in patients with breast cancer (BC). As a
predominant component of inflammasome, Nod-like receptor protein 3 (NLRP3) was found …

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high
rates of metastasis, recurrence and drug resistance, and diverse molecular and histological …

Introduction Triple-negative breast cancer (TNBC) comprises a heterogeneous group of
clinically aggressive tumors with high risk of recurrence and metastasis. Current …

Breast cancer is the most common malignancy and cause of cancer-related mortality among
women worldwide. Triple negative breast cancers (TNBC) are the most aggressive and …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive lethal malignancy that
accounts for more than 90% of pancreatic cancer diagnoses. Our research is focused on the …

Abstract 3D cell models derived from patient tumors are highly translational tools that can
recapitulate the complex genetic and molecular compositions of solid cancers and …

Unlike other types of breast cancer, triple negative breast cancer (TNBC) does not respond
to therapies targeting human epidermal growth factor receptor-2 (HER2) or hormone …

Triple-negative breast cancer (TNBC) has a more aggressive phenotype and higher
metastasis and recurrence rates than other breast cancer subtypes. TNBC currently lacks a …