Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …

Many patients with immunoglobulin A nephropathy (IgAN) progress to kidney failure even
with optimal supportive care. An improved understanding of the pathophysiology of IgAN in …

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. Recent years have witnessed significant improvements in the understanding of …

Thrombotic microangiopathy (TMA) refers to a condition caused by microvascular injury that
includes thrombosis, hemolytic anemia, and thrombocytopenia. There are two classic TMAs …

Background Complement alternative pathway (AP) activation is linked to immunoglobulin A
nephropathy (IgAN) prognosis severity, but Bb fragment's role is unclear. We examined the …

Background The aim was to study clinicopathological characteristics, risk factors and renal
outcome in IgA nephropathy (IgAN) patients with vascular lesions. Methods We enrolled a …

In glomerulopathies, endothelial dysfunction and the presence of histological vascular
lesions such as thrombotic microangiopathy, arteriolar hyalinosis, and arteriosclerosis are …

Background: IgA nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. IgAN causes end-stage kidney disease (ESKD) in 30–40% of all cases. The …

Background Thrombotic microangiopathy (TMA) occurs in immunoglobulin A nephropathy
(IgAN), and the pathogenesis is not known behind the endothelium injury. The genetic …

Background Microangiopathy (MA) lesions are not rare in immunoglobulin A nephropathy
(IgAN) and have been suggested to have a potential role in increasing risk in renal function …