[HTML][HTML] Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

Y Zhang, V Chandra, E Riquelme Sanchez… - Journal of experimental …, 2020 - rupress.org
Disclosure: Dr. Maitra reports Thrive Earlier Detection has licensed an invention from Johns
Hopkins University in which Dr. Maitra is listed as an inventor. The focus of the license is on …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

Immunogenicity of biologic therapies: causes and consequences

WH Boehncke, NC Brembilla - Expert review of clinical …, 2018 - Taylor & Francis
Introduction: Antibodies or fusion proteins termed biologics allow the targeted therapy of
diseases. Many of these agents have proven superior efficacy and safety to conventional …

Guselkumab versus secukinumab for the treatment of moderate-to-severe psoriasis (ECLIPSE): results from a phase 3, randomised controlled trial

K Reich, AW Armstrong, RG Langley, S Flavin… - The Lancet, 2019 - thelancet.com
Background Antibodies targeting interleukin (IL)-23 and IL-17A effectively treat moderate-to-
severe psoriasis. ECLIPSE is the first comparator study of an IL-23p19 inhibitor …

Recent advances in antibody‐based immunotherapy strategies for COVID‐19

A Esmaeilzadeh, S Rostami… - Journal of cellular …, 2021 - Wiley Online Library
The emergence of a new acute respiratory syndrome Coronavirus 2 (SARS‐CoV‐2), the
cause of the 2019‐nCOV disease (COVID‐19), has caused a pandemic and a global health …

Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study

J Braun, X Baraliakos, A Deodhar, D Poddubnyy… - …, 2019 - academic.oup.com
Objective To evaluate the effect of secukinumab, a fully human anti-interleukin-17A
monoclonal antibody, on efficacy, imaging outcomes, and safety through 4 years (208 …

European S3-Guideline on the systemic treatment of psoriasis vulgaris-Update Apremilast and Secukinumab-EDF in cooperation with EADV and IPC.

A Nast, PI Spuls, G Kraaij, P Gisondi… - Journal of the …, 2017 - search.ebscohost.com
The article presents a report on the updates in the European S3-Guideline on systemic
treatment of psoriasis vulgaris in cooperation with the European Academy of Dermatology …

[HTML][HTML] Potential role of IL‐17 blocking agents in the treatment of severe COVID‐19?

V Bulat, M Situm, MD Azdajic, R Likic - British journal of clinical …, 2021 - ncbi.nlm.nih.gov
After the World Health Organisation declared Coronavirus Disease 2019 (COVID-19) a
global pandemic on March 11, 2020, it became clear that health professionals worldwide …

The immunogenicity of biologic therapies

S Garcês, J Demengeot - Adverse Reactions to Biologics, 2018 - karger.com
Virtually all therapeutic proteins (biologics) elicit an immune response with the consequent
production of anti-drug antibodies (ADA). The majority of ADA to therapeutic monoclonal …

[PDF][PDF] Primary efficacy of netakimab, a novel interleukin-17 inhibitor, in the treatment of active ankylosing spondylitis in adults

S Erdes, E Nasonov, E Kunder, A Pristrom… - Clin Exp …, 2020 - academia.edu
Objective Netakimab (NTK) is a humanised monoclonal antibody targeting interleukin-17A,
previously investigated in a phase 1 trial in healthy volunteers. Here, we report the results of …