Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …

Recent studies have suggested that the intestinal microbiome plays an important role in
modulating risk of several chronic diseases, including inflammatory bowel disease, obesity …

The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention.
Bidirectional communication between gut microbes and the host can impact numerous …

Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are
elevated, regardless of the presence of obvious infection. It has been suggested to lead to …

The gut microbiota is a complex community of bacteria residing in the intestine. Animal
models have demonstrated that several factors contribute to and can significantly alter the …

Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

Prolonged high fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and
diets high in saturated fat are a risk factor for the development of human inflammatory bowel …

Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …

Obesity and its associated disorders are a major public health concern. Although obesity
has been mainly related with perturbations of the balance between food intake and energy …

The Mediterranean diet pattern is increasingly associated with improved metabolic health.
Two mechanisms by which consuming a Mediterranean diet pattern may contribute to …