[HTML][HTML] Challenges in management of VTE in children with cancer: risk factors and treatment options

N Samji, MD Bhatt, K Kulkarni - Frontiers in Pediatrics, 2022 - frontiersin.org
Venous thromboembolism (VTE) occurs in 2.1 to up to 50% of children with cancer and
contributes to long term morbidity as well as early mortality in this population. Pediatric …

Venous thromboembolism in pediatric cancer patients with central venous catheter—a systematic review and meta-analysis

RS Hansen, M Nybo, AM Hvas - Seminars in Thrombosis and …, 2021 - thieme-connect.com
Pediatric cancer patients hold an increased risk of venous thromboembolism (VTE) due to
their cancer. Central venous catheters (CVCs) further increase the VTE risk. This systematic …

Thrombosis is associated with worse survival in children with acute lymphoblastic leukemia: a report from CYP‐C

MC Pelland‐Marcotte, K Kulkarni… - American Journal of …, 2021 - Wiley Online Library
There are conflicting data about whether the development of cancer‐associated thrombo‐
embolism (TE) negatively impacts survival in children. The objective was to determine …

Development and validation of thromboembolism diagnostic algorithms in children with cancer from real-world data

U Athale, J Halton, A Gayowsky, AKC Chan… - Pediatric Research, 2024 - nature.com
Objective To evaluate the accuracy of diagnostic algorithms developed using the
International Classification of Diseases (ICD-9-CM and ICD-10-CA) diagnostic codes and …

Risk factors and clinical impact of thrombosis during induction chemotherapy for pediatric acute lymphoblastic leukemia: A report from CYP‐C

MC Pelland‐Marcotte, K Kulkarni… - American Journal of …, 2024 - Wiley Online Library
Thromboembolism (TE) is associated with reduced survival in pediatric acute lymphoblastic
leukemia (ALL). It has been hypothesized that TE might signal leukemic aggressiveness …

Venous Thromboembolic Events in Adolescent and Young Adult Patients with Acute Lymphoblastic Leukemia

SR Jones, RB Patel, MQ Rahim… - Journal of Adolescent …, 2022 - liebertpub.com
Acute venous thromboembolisms (VTEs) are serious complications that occur during acute
lymphoblastic leukemia (ALL) chemotherapy. The data elucidating risk factors for …

Safety and efficacy of direct oral anticoagulants for treatment of venous thromboembolism in pediatric oncology patients

A Scheuermann, M Liegl, P Simpson… - Journal of Pediatric …, 2023 - journals.lww.com
Methods: We performed a single-center, retrospective review of children 0 to 20 years of age
from 2012 to 2020 with malignancy and confirmed VTE, with the objective to evaluate the …

Thromboembolism in children with cancer: a retrospective multicenter study in Korea

HS Choi, HJ Kim, HJ Kang, JW Lee, HY Shin… - Journal of Thrombosis …, 2019 - Springer
Thromboembolism (TE) is a major cause of morbidity and mortality in adult cancer patients;
however, there is a lack of sufficient knowledge on TE in pediatric cancer patients. We aimed …

Use of tissue plasminogen activator as a surrogate measure for central venous catheter dysfunction and survival outcome in children with cancer: a population-based …

Z Forbrigger, K Kulkarni - Pediatric Hematology and Oncology, 2020 - Taylor & Francis
Central venous catheter (CVC) dysfunction is often associated with thrombosis, which in turn
has been linked with poorer survival outcomes in cancer patients. Our objective was to …

Study of Clinical and Prothrombotic Gene Mutation as Predictors of Thromboembolism in Pediatric Cancer

SA Elshwadfy, MA Hesham… - Zagazig University …, 2023 - journals.ekb.eg
Background: Thromboembolism is a well-recognized complication in children with cancer
and associated with chronic morbidity, delay of treatment, adverse events associated with …