[HTML][HTML] Methylenetetrahydrofolate reductase A1298C polymorphism and major depressive disorder

K Cho, ZM Amin, J An, KA Rambaran, TB Johnson… - Cureus, 2017 - ncbi.nlm.nih.gov
Major depressive disorder (MDD) is a disorder that carries significant psychosocial and
economic implications. Research efforts have focused on identifying biomarkers that can aid …

[HTML][HTML] Multiple adverse drug reactions and genetic polymorphism testing: A case report with negative result

AL Arellano, M Martin-Subero, M Monerris, A LLerena… - Medicine, 2017 - journals.lww.com
3 Discussion As a result, no metabolic deficiencies for CYP2D6 were confirmed in the
pharmacogenetic test. The main reason that could explain those results could be the limited …

[HTML][HTML] Putting Out the Fire: The Relationship of Pharmacogenetics and Proton Pump Inhibitors for the Treatment of Gastroesophageal Reflux Disease

CL Zheng, SK Alzghari - Cureus, 2018 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) are a mainstay treatment for gastroesophageal reflux disease
(GERD) and are mainly metabolized by CYP2C19 in the liver. However, several …

[HTML][HTML] An unnecessary pain: using pharmacogenetics for statin-related skeletal muscle toxicity

SK Alzghari - Cureus, 2018 - ncbi.nlm.nih.gov
Statins are an important class of medications in reducing the risk of cardiovascular events as
well as overall mortality. However, a well-known adverse effect of statins is skeletal muscle …