[HTML][HTML] ROS-responsive drug delivery systems for biomedical applications

W Tao, Z He - asian journal of pharmaceutical sciences, 2018 - Elsevier
In the field of biomedicine, stimuli-responsive drug delivery systems (DDSs) have become
increasingly popular due to their site-specific release ability in response to a certain …

[HTML][HTML] Vanillin: A food additive with multiple biological activities

A Olatunde, A Mohammed, MA Ibrahim… - European Journal of …, 2022 - Elsevier
Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a known natural aromatic
flavouring agent and the major component of vanilla extracted from cured vanilla pods …

Antimicrobial activity and composition profile of grape (Vitis vinifera) pomace extracts obtained by supercritical fluids

DA Oliveira, AA Salvador, A Smânia Jr… - Journal of …, 2013 - Elsevier
The possibility of increasing the aggregated value of the huge amount of residues generated
by wineries around the world foment studies using the grape pomace–the residue from the …

Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy

JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis

BB Aggarwal, ME Van Kuiken, LH Iyer… - Experimental …, 2009 - journals.sagepub.com
Despite the fact cancer is primarily a preventable disease, recent statistics indicate cancer
will become the number one killer worldwide in 2010. Since certain cancers are more …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Lung cancer stem cells and cancer stem cell-targeting natural compounds

A Maiuthed, W Chantarawong… - Anticancer …, 2018 - ar.iiarjournals.org
The novel information regarding molecular and translational research have created a
paradigm shift in the understanding of lung cancer biology, revealing the more precise target …

Inflammation-responsive antioxidant nanoparticles based on a polymeric prodrug of vanillin

J Kwon, J Kim, S Park, G Khang, PM Kang… - …, 2013 - ACS Publications
Oxidative stress is induced by accumulation of hydrogen peroxide (H2O2), and therefore,
H2O2 could serve as a potential biomarker of various oxidative stress-associated …

Overview of the role of vanillin on redox status and cancer development

DP Bezerra, AKN Soares… - Oxidative medicine and …, 2016 - Wiley Online Library
Bioactive natural products play critical roles in modern drug development, especially
anticancer agents. It has been widely reported that various pharmacological activities of …

Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin

KL Ho, LS Yazan, N Ismail, M Ismail - Cancer epidemiology, 2009 - Elsevier
Background: Vanillin is responsible for the flavor and smell of vanilla, a widely used
flavoring agent. Previous studies showed that vanillin could enhance the repair of mutations …