Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques

KV Kovtunov, EV Pokochueva… - Chemistry–An Asian …, 2018 - Wiley Online Library
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

Heterogeneous Catalysis and Parahydrogen‐Induced Polarization

EV Pokochueva, DB Burueva, OG Salnikov… - …, 2021 - Wiley Online Library
Parahydrogen‐induced polarization with heterogeneous catalysts (HET‐PHIP) has been a
subject of extensive research in the last decade since its first observation in 2007. While …

Ultra-low-cost disposable hand-held clinical-scale propane gas hyperpolarizer for pulmonary magnetic resonance imaging sensing

NM Ariyasingha, A Samoilenko, JR Birchall… - ACS …, 2023 - ACS Publications
Hyperpolarized magnetic resonance imaging (MRI) contrast agents are revolutionizing the
field of biomedical imaging. Hyperpolarized Xe-129 was recently FDA approved as an …

Open-Source Automated Parahydrogen Hyperpolarizer for Molecular Imaging Using 13C Metabolic Contrast Agents

AM Coffey, RV Shchepin, ML Truong… - Analytical …, 2016 - ACS Publications
An open-source hyperpolarizer producing 13C hyperpolarized contrast agents using
parahydrogen induced polarization (PHIP) for biomedical and other applications is …

Strong Metal–Support Interactions Enhance the Pairwise Selectivity of Parahydrogen Addition over Ir/TiO2

EW Zhao, H Zheng, K Ludden, Y Xin… - Acs …, 2016 - ACS Publications
The effects of strong metal–support interactions (SMSI) on the pairwise selectivity of propene
hydrogenation over metal-oxide-supported Ir nanoparticles were investigated using …

[HTML][HTML] Perspectives for hyperpolarisation in compact NMR

ME Halse - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Nuclear magnetic resonance (NMR) is one of the most powerful analytical techniques
currently available, with applications in fields ranging from synthetic chemistry to clinical …

Transfer of SABRE-derived hyperpolarization to spin-1/2 heteronuclei

AN Pravdivtsev, AV Yurkovskaya, H Zimmermann… - Rsc Advances, 2015 - pubs.rsc.org
In this paper, we describe a method of hyper-polarizing “insensitive” Nuclear Magnetic
Resonance (NMR) nuclei by exploiting the SABRE (Signal Amplification By Reversible …