Urine is a valuable diagnostic medium and, with the discovery of urinary extracellular
vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed …

Exosomes, known as nanometer‐sized vesicles (30–200 nm), are secreted by many types of
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …

To develop effective disease-modifying therapies for neurodegenerative diseases, reliable
markers of diagnosis, disease activity and progression are a research priority. The fact that …

Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

Aging is consistently reported as the most important independent risk factor for
neurodegenerative diseases. As life expectancy has significantly increased during the last …

Background Leucine‐rich repeat kinase 2 (LRRK2) inhibition is a promising therapeutic
approach for the treatment of Parkinson's disease (PD). Objective The aim of this study was …

Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Extracellular vesicles (EVs, including exosomes) are implicated in many aspects of nervous
system development and function, including regulation of synaptic communication, synaptic …

Growing evidence indicates that small extracellular vesicles, called exosomes, are
prominent mediators of neurodegenerative diseases such as prion, Alzheimer's and …

Progress in developing disease-modifying therapies in Parkinson's disease (PD) can only
be achieved through reliable objective markers that help to identify subjects at risk. This …