Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Skin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated.
Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue …

The last few years have seen the development of numerous deep learning-based protein–
ligand docking methods. They offer huge promise in terms of speed and accuracy. However …

Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …

Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

Cancer accounts for numerous deaths each year, and it is one of the most common causes
of death worldwide, despite many breakthroughs in the discovery of novel anticancer …

Nitrogen heterocycles are among the most significant structural components of
pharmaceuticals. Analysis of our database of US FDA approved drugs reveals that 59% of …

Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

This review presents the main aspects related to pharmacokinetic properties, which are
essential for the efficacy and safety of drugs. This topic is very important because the …

The monovalent methyl group is derived from methane through the removal of a hydrogen
atom, 1 and its etymology is directly related to the discovery of methanol. 2 The first reports …