Mitochondrial dysfunction and the inflammatory response

MJ López-Armada, RR Riveiro-Naveira… - Mitochondrion, 2013 - Elsevier
Inflammation has been linked to multiple degenerative and acute diseases as well as the
aging process. Moreover, mitochondrial alterations play a central role in these processes …

Laboratory markers predicting severity of acute pancreatitis

SM Staubli, D Oertli, CA Nebiker - Critical reviews in clinical …, 2015 - Taylor & Francis
Acute pancreatitis (AP) is an inflammatory disease of highly variable severity, ranging from
mild cases with low mortality to severe cases with high mortality. Numerous biomarkers have …

Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation

EP Dellinger, CE Forsmark, P Layer, P Lévy… - Annals of …, 2012 - journals.lww.com
Objective: To develop a new international classification of acute pancreatitis severity on the
basis of a sound conceptual framework, comprehensive review of published evidence, and …

Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis

F Tse, Y Yuan - Cochrane database of systematic reviews, 2012 - cochranelibrary.com
Background The role and timing of endoscopic retrograde cholangiopancreatography
(ERCP) in acute gallstone pancreatitis remains controversial. A number of clinical trials and …

Neutrophil-lymphocyte ratio as a predictor of adverse outcomes of acute pancreatitis

B Azab, N Jaglall, JP Atallah, A Lamet, V Raja-Surya… - Pancreatology, 2011 - Elsevier
Background: Most acute pancreatitis risk scoring systems use total white blood cell counts
(WBC) as one of the riskfactors. Thevalue of the neutrophil-lymphocyte ratio (NLR) to predict …

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis

R Hoque, M Sohail, A Malik, S Sarwar, Y Luo, A Shah… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Acute pancreatitis is characterized by early activation of
intracellular proteases followed by acinar cell death and inflammation. Activation of damage …

[HTML][HTML] Early phase of acute pancreatitis: assessment and management

V Phillip, JM Steiner, H Algül - World journal of gastrointestinal …, 2014 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a potentially life-threatening disease with a wide spectrum of
severity. The overall mortality of AP is approximately 5%. According to the revised Atlanta …

Stigma, biomarkers, and algorithmic bias: recommendations for precision behavioral health with artificial intelligence

CG Walsh, B Chaudhry, P Dua, KW Goodman… - JAMIA …, 2020 - academic.oup.com
Effective implementation of artificial intelligence in behavioral healthcare delivery depends
on overcoming challenges that are pronounced in this domain. Self and social stigma …

Ranson score to stratify severity in Acute Pancreatitis remains valid–Old is gold

Y Ong, VG Shelat - Expert Review of Gastroenterology & …, 2021 - Taylor & Francis
Introduction: Acute pancreatitis (AP) is a common gastrointestinal disease with a wide
spectrum of severity and morbidity. Developed in 1974, the Ranson score was the first …

[HTML][HTML] Diagnosis, severity stratification and management of adult acute pancreatitis–current evidence and controversies

KS Chan, VG Shelat - World Journal of Gastrointestinal Surgery, 2022 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a disease spectrum ranging from mild to severe with an
unpredictable natural course. Majority of cases (80%) are mild and self-limiting. However …