Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an
imbalance in cell fate decision. IR is able to regulate several genes and factors involved in …

Radiation therapy is one of the most common treatment strategies for thorax malignancies.
One of the considerable limitations of this therapy is its toxicity to normal tissue. The lung is …

Introduction: The lysyl oxidase family of enzymes is classically known as being required for
connective tissue maturation by oxidizing lysine residues in elastin and lysine and …

Purpose: Terrorist attacks, with their intent to maximize psychological and economic damage
as well as inflicting sickness and death on given targeted populations, are an ever-growing …

Radiation-induced pulmonary fibrosis (RIPF), a late adverse event of radiation therapy, is
characterized by infiltration of inflammatory cells, progressive loss of alveolar structure …

The implementation of novel cancer immunotherapies in the form of immune checkpoint
blockers represents a major advancement in the treatment of cancer, and has renewed …

There is an ongoing and significant need for radiation countermeasures to reduce
morbidities and mortalities associated with exposure of the heart and lungs from a …

Purpose: Radiation-induced lung injuries (RILI), namely radiation pneumonitis and/or
fibrosis, are dose-limiting outcomes following treatment for thoracic cancers. As part of a …

We aim to investigate the effects of adipose‐derived stem cells (ASCs) transplantation on
irradiation‐induced skeletal muscle fibrosis. Sixty‐four rabbits were randomly divided into …

Background Inflammatory reactions induced by alveolar macrophages and excessive
fibroblast activation lead to pulmonary fibrosis in silicosis. The endothelial-mesenchymal …