Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss

S Pouwels, N Sakran, Y Graham, A Leal, T Pintar… - BMC endocrine …, 2022 - Springer
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects
of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public …

Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020

K Tokushige, K Ikejima, M Ono, Y Eguchi… - Journal of …, 2021 - Springer
Nonalcoholic fatty liver disease (NAFLD) has become a serious public health issue not only
in Western countries but also in Japan. Within the wide spectrum of NAFLD, nonalcoholic …

Bariatric surgery provides long-term resolution of nonalcoholic steatohepatitis and regression of fibrosis

G Lassailly, R Caiazzo, LC Ntandja-Wandji, V Gnemmi… - Gastroenterology, 2020 - Elsevier
Background and Aims Studies are needed to determine the long-term effects of bariatric
surgery for patients with nonalcoholic steatohepatitis (NASH). We evaluated sequential liver …

Assessment of hepatic steatosis by controlled attenuation parameter using the M and XL probes: an individual patient data meta-analysis

D Petroff, V Blank, PN Newsome, CS Voican… - The Lancet …, 2021 - thelancet.com
Background Diagnostic tools for liver disease can now include estimation of the grade of
hepatic steatosis (S0 to S3). Controlled attenuation parameter (CAP) is a non-invasive …

Magnetic resonance elastography vs transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven …

CC Park, P Nguyen, C Hernandez, R Bettencourt… - Gastroenterology, 2017 - Elsevier
Background & Aims Magnetic resonance imaging (MRI) techniques and ultrasound-based
transient elastography (TE) can be used in noninvasive diagnosis of fibrosis and steatosis in …

[PDF][PDF] A machine learning approach enables quantitative measurement of liver histology and disease monitoring in NASH

A Taylor‐Weiner, H Pokkalla, L Han, C Jia, R Huss… - …, 2021 - Wiley Online Library
Background and Aims Manual histological assessment is currently the accepted standard for
diagnosing and monitoring disease progression in NASH, but is limited by variability in …

Determinants of fibrosis progression and regression in NASH

D Schuppan, R Surabattula, XY Wang - Journal of hepatology, 2018 - Elsevier
Cirrhosis has become the major liver-related clinical endpoint in non-alcoholic
steatohepatitis (NASH). However, progression to cirrhosis is less predictable in NASH than …

[HTML][HTML] Imaging biomarkers of NAFLD, NASH, and fibrosis

V Ajmera, R Loomba - Molecular metabolism, 2021 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic entity that
requires a liver biopsy assessment to diagnose the progressive form of NAFLD called non …

[PDF][PDF] Optimal threshold of controlled attenuation parameter with MRI‐PDFF as the gold standard for the detection of hepatic steatosis

C Caussy, MH Alquiraish, P Nguyen… - …, 2018 - Wiley Online Library
The optimal threshold of controlled attenuation parameter (CAP) for the detection of hepatic
steatosis using both M and XL probe is unknown in nonalcoholic fatty liver disease (NAFLD) …

[HTML][HTML] KASL clinical practice guidelines: management of nonalcoholic fatty liver disease

SH Kang, HW Lee, JJ Yoo, Y Cho, SU Kim… - Clinical and …, 2021 - ncbi.nlm.nih.gov
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing rapidly worldwide
as the obese and diabetic populations increase, and it has been estimated to be 20–30% in …