[HTML][HTML] The role of Neuropilin-1 in COVID-19

BS Mayi, JA Leibowitz, AT Woods, KA Ammon… - PLoS …, 2021 - journals.plos.org
Neuropilin-1 (NRP-1), a member of a family of signaling proteins, was shown to serve as an
entry factor and potentiate SARS Coronavirus 2 (SARS-CoV-2) infectivity in vitro. This cell …

Mechanisms and regulation of endothelial VEGF receptor signalling

M Simons, E Gordon, L Claesson-Welsh - Nature reviews Molecular …, 2016 - nature.com
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

Diverse roles for VEGF-A in the nervous system

F Mackenzie, C Ruhrberg - Development, 2012 - journals.biologists.com
Vascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood
vessel growth. However, evidence has emerged that VEGF-A also promotes a wide range of …

VEGF signaling inside vascular endothelial cells and beyond

A Eichmann, M Simons - Current opinion in cell biology, 2012 - Elsevier
Vascular endothelial growth factor-A (VEGF-A) has long been recognized as the key
regulator of vascular development and function in health and disease. VEGF is a secreted …

[HTML][HTML] SEMA3A, a Gene Involved in Axonal Pathfinding, Is Mutated in Patients with Kallmann Syndrome

NK Hanchate, P Giacobini, P Lhuillier, J Parkash… - 2012 - journals.plos.org
Kallmann syndrome (KS) associates congenital hypogonadism due to gonadotropin-
releasing hormone (GnRH) deficiency and anosmia. The genetics of KS involves various …

[HTML][HTML] VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma

RH Foxton, A Finkelstein, S Vijay… - The American journal of …, 2013 - Elsevier
Vascular endothelial growth factor A (VEGF-A) is a validated therapeutic target in several
angiogenic-and vascular permeability–related pathological conditions, including certain …

[HTML][HTML] Pharmacokinetics of bevacizumab and its effects on serum VEGF and IGF-1 in infants with retinopathy of prematurity

L Kong, AR Bhatt, AB Demny, DK Coats… - … & visual science, 2015 - iovs.arvojournals.org
Purpose.: To measure serum levels of bevacizumab and to compare serum levels of free
vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) in infants …

[HTML][HTML] Vascularisation of the central nervous system

M Tata, C Ruhrberg, A Fantin - Mechanisms of development, 2015 - Elsevier
The developing central nervous system (CNS) is vascularised through the angiogenic
invasion of blood vessels from a perineural vascular plexus, followed by continued sprouting …

Cleaved caspase-3 transcriptionally regulates angiogenesis-promoting chemotherapy resistance

A Bernard, S Chevrier, F Beltjens, M Dosset, E Viltard… - Cancer research, 2019 - AACR
Caspases are well known for their role in apoptosis. Recently, nonapoptotic roles of
caspases have been identified, however, these noncanonical roles are not well documented …

Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability

A Plein, A Fantin, C Ruhrberg - Microcirculation, 2014 - Wiley Online Library
The formation of the cardiovasculature, consisting of both the heart and blood vessels, is a
critical step in embryonic development and relies on three processes termed …