Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

On the influence of several factors on pathway enrichment analysis

S Mubeen, A Tom Kodamullil… - Briefings in …, 2022 - academic.oup.com
Pathway enrichment analysis has become a widely used knowledge-based approach for the
interpretation of biomedical data. Its popularity has led to an explosion of both enrichment …

Functional enrichment analysis of regulatory elements

A Garcia-Moreno, R López-Domínguez… - Biomedicines, 2022 - mdpi.com
Statistical methods for enrichment analysis are important tools to extract biological
information from omics experiments. Although these methods have been widely used for the …

miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems

F Kern, T Fehlmann, J Solomon, L Schwed… - Nucleic acids …, 2020 - academic.oup.com
Gene set enrichment analysis has become one of the most frequently used applications in
molecular biology research. Originally developed for gene sets, the same statistical …

Popularity and performance of bioinformatics software: the case of gene set analysis

C Xie, S Jauhari, A Mora - BMC bioinformatics, 2021 - Springer
Abstract Background Gene Set Analysis (GSA) is arguably the method of choice for the
functional interpretation of omics results. The following paper explores the popularity and the …

In silico Analysis Excavates A Novel Competing Endogenous RNA Subnetwork in Adolescent Idiopathic Scoliosis

HM Li, Y Liu, JY Ding, R Zhang, XY Liu… - Frontiers in medicine, 2020 - frontiersin.org
Background and Objective: Adolescent idiopathic scoliosis (AIS) is a complex three-
dimensional deformity of the spine. Mesenchymal stem cells (MSCs) regulate bone mass …

Construction of a novel mRNA–miRNA–lncRNA/circRNA triple subnetwork associated with immunity and aging in intervertebral disc degeneration

W Liu, HM Li, G Bai - Nucleosides, Nucleotides & Nucleic Acids, 2024 - Taylor & Francis
Objective Intervertebral disk degeneration (IVDD) is one of the most common causes of low
back pain. However, in the etiology of IVDD, the specific method by which nucleus pulposus …

GSA Central—A web platform to perform, learn, and discuss gene set analysis

X Huang, X Lu, C Xie, S Jauhari, Z Xie, S Mei… - Frontiers in …, 2022 - frontiersin.org
Gene Set Analysis (GSA) is one of the most commonly used strategies to analyze omics
data. Hundreds of GSA-related papers have been published, giving birth to a GSA field in …

[PDF][PDF] Efficient gene set analysis of high-throughput data

PP Mishra - helda.helsinki.fi
A Statistical distribution models fitted on the empirical null distribution generated by GSA
and Allez with p53 data and their results............... 133 B Correlation of different p-value …