Curcumin analogues and their hybrid molecules as multifunctional drugs

SA Noureddin, RM El-Shishtawy, KO Al-Footy - European journal of …, 2019 - Elsevier
Abstract Curcumin (diferuloylmethane or 1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-
heptadiene-3, 5-dione) is an interesting compound that is characterized by a special …

ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

Bioactive compounds: natural defense against cancer?

S Subramaniam, KR Selvaduray, AK Radhakrishnan - Biomolecules, 2019 - mdpi.com
Cancer is a devastating disease that has claimed many lives. Natural bioactive agents from
plants are gaining wide attention for their anticancer activities. Several studies have found …

Curcumin exerts a protective effect against premature ovarian failure in mice

Z Yan, Y Dai, H Fu, Y Zheng, D Bao… - Journal of …, 2018 - jme.bioscientifica.com
This study was designed to investigate the protective effect of curcumin against d-galactose
(d-gal)-induced premature ovarian failure (POF) in mice. A mouse POF model was induced …

Mechanism insights of curcumin and its analogues in cancer: An update

P Joshi, K Verma, D Kumar Semwal… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis

S Sun, H Fang - Journal of Ovarian Research, 2021 - Springer
Background Curcumin has a potential therapeutic role in ovarian cancer. However, whether
curcumin plays anti-cancer role in ovarian cancer by mediating the circular RNA …

[HTML][HTML] Basic research on curcumin in cervical cancer: Progress and perspectives

X Zhang, L Zhu, X Wang, H Zhang, L Wang… - Biomedicine & …, 2023 - Elsevier
Curcumin is a polyphenolic substance extracted from plants such as Curcuma longa,
Curcuma zedoaria, and radix curcumae, and it has attracted much attention because of the …

Curcumin suppresses cisplatin resistance development partly via modulating extracellular vesicle-mediated transfer of MEG3 and miR-214 in ovarian cancer

J Zhang, J Liu, X Xu, L Li - Cancer chemotherapy and pharmacology, 2017 - Springer
Purpose To investigate how curcumin alters the extracellular vesicles'(EVs) capability to ship
drug resistance in ovarian cancer. Methods The EVs from cisplatin-resistant A2780cp cells …

[HTML][HTML] Curcumin as tyrosine kinase inhibitor in cancer treatment

A Golonko, H Lewandowska, R Świsłocka… - European Journal of …, 2019 - Elsevier
Curcumin is a natural substance known for ages, exhibiting a multidirectional effect in
cancer prevention and adjuvant cancer therapies. The great advantage of using …

Molecular mechanisms of curcumin and its analogs in colon cancer prevention and treatment

C Selvam, SL Prabu, BC Jordan, Y Purushothaman… - Life sciences, 2019 - Elsevier
Colorectal cancer remains to be the most prevalent malignancy in humans and 1.5 million
men and women living in the United States are diagnosed with colorectal cancer, with a …