Cu-related agents for cancer therapies
C Wang, X Yang, C Dong, K Chai, J Ruan… - Coordination Chemistry …, 2023 - Elsevier
As an indispensable micronutrient, copper (Cu) plays an important role in promoting
metabolism and maintaining various basic biological functions. Copper homeostasis in the …
metabolism and maintaining various basic biological functions. Copper homeostasis in the …
Recent advances and therapeutic journey of Schiff base complexes with selected metals (Pt, Pd, Ag, Au) as potent anticancer agents: A review
S Khan, FA Alhumaydhi, MM Ibrahim… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Schiff bases and their transition metal complexes play an important role in the field of
medicine, in particular in the treatment of cancer. Since the discovery of the cisplatin …
medicine, in particular in the treatment of cancer. Since the discovery of the cisplatin …
Green carbon–carbon homocoupling of terminal alkynes by a silica supported Cu (ii)-hydrazone coordination compound
A Cu (II) complex,[Cu (HL)(NO3)(CH3OH)]· CH3OH (1), was obtained by the reaction of Cu
(NO3) 2· 3H2O and H2L in methanol solvent (H2L is (E)-4-amino-N′-(2-hydroxy-3 …
(NO3) 2· 3H2O and H2L in methanol solvent (H2L is (E)-4-amino-N′-(2-hydroxy-3 …
Finding new molecular targets of two copper (II)-hydrazone complexes on triple-negative breast cancer cells using mass-spectrometry-based quantitative proteomics
Breast cancer is the most common cancer in women, with a high incidence estimated to
reach 2.3 million by 2030. Triple-Negative Breast Cancer (TNBC) is the greatest invasive …
reach 2.3 million by 2030. Triple-Negative Breast Cancer (TNBC) is the greatest invasive …
[HTML][HTML] Antiproliferative activity of two copper (II) complexes on colorectal cancer cell models: Impact on ROS production, apoptosis induction and NF-κB inhibition
The main goal of this work was to screen the antiproliferative activity and mechanism of
actions of two copper complexes:[Cu (dmp) 2 (CH 3 CN)] 2+(1) and [Cu (phen) 2 (CH 3 CN)] …
actions of two copper complexes:[Cu (dmp) 2 (CH 3 CN)] 2+(1) and [Cu (phen) 2 (CH 3 CN)] …
N-Naphthoyl Thiourea Derivatives: An Efficient Ultrasonic-Assisted Synthesis, Reaction, and In Vitro Anticancer Evaluations
This work demonstrates the optimization of an efficient, mild, and environmentally friendly
synthetic approach to access a diverse library of N-naphthoyl thioureas. These derivatives …
synthetic approach to access a diverse library of N-naphthoyl thioureas. These derivatives …
Hydrazylpyridine salicylaldehyde–copper (ii)–1, 10-phenanthroline complexes as potential anticancer agents: synthesis, characterization and anticancer evaluation
Y Chen, Z Ke, L Yuan, M Liang, S Zhang - Dalton Transactions, 2023 - pubs.rsc.org
We synthesized and analyzed nine unique copper (II) hydrazylpyridine salicylaldehyde and
1, 10-phenanthroline complexes,[Cu (L1a)(phen)](Cugdupt1),[Cu (L2a)(phen)]·(CH3CN) …
1, 10-phenanthroline complexes,[Cu (L1a)(phen)](Cugdupt1),[Cu (L2a)(phen)]·(CH3CN) …
Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models
L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
8-hydroxyquinoline-N-oxide copper (II)-and zinc (II)-phenanthroline and bipyridine coordination compounds: Design, synthesis, structures, and antitumor evaluation
LQ Du, CJ Zeng, DY Mo, QP Qin, MX Tan… - Journal of Inorganic …, 2024 - Elsevier
Fourteen novel tumor-targeting copper (II) and zinc (II) complexes,[Cu (ONQ)(QD1)(NO 3)]·
CH 3 OH (NQ3),[Cu (ONQ)(QD2)(NO 3)](NQ2),[Cu (NQ)(QD2) Cl](NQ3),[Cu (ONQ)(QD1) …
CH 3 OH (NQ3),[Cu (ONQ)(QD2)(NO 3)](NQ2),[Cu (NQ)(QD2) Cl](NQ3),[Cu (ONQ)(QD1) …
Response of ancillary azide ligand in designing a 1D copper (II) polymeric complex along with the introduction of high DNA-and HAS-binding efficacy, leading to …
A new versatile azide-bridged polymeric Cu (II) complex, namely,[Cu (L)(μ1, 3-N3)]∞(1),
was synthesized utilizing an N, N, O-donor piperidine-based Schiff base ligand (E)-4-bromo …
was synthesized utilizing an N, N, O-donor piperidine-based Schiff base ligand (E)-4-bromo …