Vascularization strategies of engineered tissues and their application in cardiac regeneration
The primary function of vascular networks is to transport blood and deliver oxygen and
nutrients to tissues, which occurs at the interface of the microvasculature. Therefore, the …
nutrients to tissues, which occurs at the interface of the microvasculature. Therefore, the …
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
Cell-based therapy for prevention and reversal of myocardial remodeling
V Karantalis, W Balkan, IH Schulman… - American Journal …, 2012 - journals.physiology.org
Although pharmacological and interventional advances have reduced the morbidity and
mortality of ischemic heart disease, there is an ongoing need for novel therapeutic strategies …
mortality of ischemic heart disease, there is an ongoing need for novel therapeutic strategies …
Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction
C Mauritz, A Martens, SV Rojas, T Schnick… - European heart …, 2011 - academic.oup.com
Aims Induced pluripotent stem cell (iPSC)-derived cardiovascular progenitor cells represent
a suitable autologous cell source for myocardial regeneration as they have the capability to …
a suitable autologous cell source for myocardial regeneration as they have the capability to …
A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells
H Fonoudi, H Ansari, S Abbasalizadeh… - Stem cells …, 2015 - academic.oup.com
Recent advances in the generation of cardiomyocytes (CMs) from human pluripotent stem
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …
In Vivo Tracking and 1H/19F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate/Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac …
C Constantinides, P Basnett… - … applied materials & …, 2018 - ACS Publications
Medium-chain length polyhydroxyalkanoates (MCL-PHAs) have demonstrated exceptional
properties for cardiac tissue engineering (CTE) applications. Despite prior work on MCL …
properties for cardiac tissue engineering (CTE) applications. Despite prior work on MCL …
Electroconductive graphene-containing polymeric patch: a promising platform for future cardiac repair
A Talebi, S Labbaf, F Karimzadeh… - ACS Biomaterials …, 2020 - ACS Publications
Myocardial infarction (MI) is one of the leading causes of death worldwide. The
complications associated with MI can lead to the formation of nonconductive fibrous scar …
complications associated with MI can lead to the formation of nonconductive fibrous scar …
Geometric control of cardiomyogenic induction in human pluripotent stem cells
CL Bauwens, H Song, N Thavandiran… - … Engineering Part A, 2011 - liebertpub.com
Although it has been observed that aggregate size affects cardiac development, an
incomplete understanding of the cellular mechanisms underlying human pluripotent stem …
incomplete understanding of the cellular mechanisms underlying human pluripotent stem …
Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells
WZ Zhu, B Van Biber, MA Laflamme - Human Pluripotent Stem Cells …, 2011 - Springer
The availability of human cardiomyocytes derived from embryonic stem cells (ESCs) has
generated considerable excitement, as these cells are an excellent model system for …
generated considerable excitement, as these cells are an excellent model system for …
Engineered biomaterials to enhance stem cell‐based cardiac tissue engineering and therapy
Cardiovascular disease is a leading cause of death worldwide. Since adult cardiac cells are
limited in their proliferation, cardiac tissue with dead or damaged cardiac cells downstream …
limited in their proliferation, cardiac tissue with dead or damaged cardiac cells downstream …