Vascularization strategies of engineered tissues and their application in cardiac regeneration

X Sun, W Altalhi, SS Nunes - Advanced drug delivery reviews, 2016 - Elsevier
The primary function of vascular networks is to transport blood and deliver oxygen and
nutrients to tissues, which occurs at the interface of the microvasculature. Therefore, the …

Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts

Y Tan, RC Coyle, RW Barrs, SE Silver, M Li… - Science …, 2023 - science.org
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Cell-based therapy for prevention and reversal of myocardial remodeling

V Karantalis, W Balkan, IH Schulman… - American Journal …, 2012 - journals.physiology.org
Although pharmacological and interventional advances have reduced the morbidity and
mortality of ischemic heart disease, there is an ongoing need for novel therapeutic strategies …

Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction

C Mauritz, A Martens, SV Rojas, T Schnick… - European heart …, 2011 - academic.oup.com
Aims Induced pluripotent stem cell (iPSC)-derived cardiovascular progenitor cells represent
a suitable autologous cell source for myocardial regeneration as they have the capability to …

A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells

H Fonoudi, H Ansari, S Abbasalizadeh… - Stem cells …, 2015 - academic.oup.com
Recent advances in the generation of cardiomyocytes (CMs) from human pluripotent stem
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …

In Vivo Tracking and 1H/19F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate/Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac …

C Constantinides, P Basnett… - … applied materials & …, 2018 - ACS Publications
Medium-chain length polyhydroxyalkanoates (MCL-PHAs) have demonstrated exceptional
properties for cardiac tissue engineering (CTE) applications. Despite prior work on MCL …

Electroconductive graphene-containing polymeric patch: a promising platform for future cardiac repair

A Talebi, S Labbaf, F Karimzadeh… - ACS Biomaterials …, 2020 - ACS Publications
Myocardial infarction (MI) is one of the leading causes of death worldwide. The
complications associated with MI can lead to the formation of nonconductive fibrous scar …

Geometric control of cardiomyogenic induction in human pluripotent stem cells

CL Bauwens, H Song, N Thavandiran… - … Engineering Part A, 2011 - liebertpub.com
Although it has been observed that aggregate size affects cardiac development, an
incomplete understanding of the cellular mechanisms underlying human pluripotent stem …

Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells

WZ Zhu, B Van Biber, MA Laflamme - Human Pluripotent Stem Cells …, 2011 - Springer
The availability of human cardiomyocytes derived from embryonic stem cells (ESCs) has
generated considerable excitement, as these cells are an excellent model system for …

Engineered biomaterials to enhance stem cell‐based cardiac tissue engineering and therapy

A Hasan, R Waters, B Roula, R Dana… - Macromolecular …, 2016 - Wiley Online Library
Cardiovascular disease is a leading cause of death worldwide. Since adult cardiac cells are
limited in their proliferation, cardiac tissue with dead or damaged cardiac cells downstream …