MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
Deep-belief network for predicting potential miRNA-disease associations
MicroRNA (miRNA) plays an important role in the occurrence, development, diagnosis and
treatment of diseases. More and more researchers begin to pay attention to the relationship …
treatment of diseases. More and more researchers begin to pay attention to the relationship …
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate-and tissue-specific microRNAs
E Londin, P Loher, AG Telonis… - Proceedings of the …, 2015 - National Acad Sciences
Two decades after the discovery of the first animal microRNA (miRNA), the number of
miRNAs in animal genomes remains a vexing question. Here, we report findings from …
miRNAs in animal genomes remains a vexing question. Here, we report findings from …
WBSMDA: within and between score for MiRNA-disease association prediction
Increasing evidences have indicated that microRNAs (miRNAs) are functionally associated
with the development and progression of various complex human diseases. However, the …
with the development and progression of various complex human diseases. However, the …
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
Semi-supervised learning for potential human microRNA-disease associations inference
X Chen, GY Yan - Scientific reports, 2014 - nature.com
MicroRNAs play critical role in the development and progression of various diseases.
Predicting potential miRNA-disease associations from vast amount of biological data is an …
Predicting potential miRNA-disease associations from vast amount of biological data is an …
LRSSLMDA: Laplacian regularized sparse subspace learning for MiRNA-disease association prediction
Predicting novel microRNA (miRNA)-disease associations is clinically significant due to
miRNAs' potential roles of diagnostic biomarkers and therapeutic targets for various human …
miRNAs' potential roles of diagnostic biomarkers and therapeutic targets for various human …
An analysis of human microRNA and disease associations
It has been reported that increasingly microRNAs are associated with diseases. However,
the patterns among the microRNA-disease associations remain largely unclear. In this study …
the patterns among the microRNA-disease associations remain largely unclear. In this study …
RWRMDA: predicting novel human microRNA–disease associations
X Chen, MX Liu, GY Yan - Molecular BioSystems, 2012 - pubs.rsc.org
Recently, more and more research has shown that microRNAs (miRNAs) play critical roles
in the development and progression of various diseases, but it is not easy to predict potential …
in the development and progression of various diseases, but it is not easy to predict potential …