Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …

Rat aorta assay provides a low cost and rapid platform, especially for preclinical in vivo
models. The signaling pathways of the analog on the vessels could be evaluated separately …

Background/Aims: Elevated production of reactive oxygen species (ROS) is linked to
endothelial dysfunction and is one of the key contributors to the pathogenesis of diabetic …

Abstract Angiotensin-(1–9)[Ang-(1–9)] is a peptide of the non-canonical renin-angiotensin
system (RAS) synthesized from angiotensin I by the monopeptidase angiotensin-converting …

Abstract Angiotensin-(19), a peptide of the non-classical renin angiotensin system, has been
shown to prevent and revert hypertension and cardiac hypertrophy. We hypothetized that …

New Findings What is the central question of this study? Variations in genes are considered
to be molecular determinants maintaining the expression of the slow or fast myosin heavy …

Angiotensin II receptor type 2 (AT 2) agonists have been shown to limit brain ischemic insult
and to improve its outcome. The activation of AT 2 was also linked to induced neuronal …

Ofrece la cobertura más actualizada sobre diabetes, síndrome metabólico, trastornos óseos
metabólicos, obesidad, enfermedad tiroidea, trastornos testiculares, trastornos …

The renin-angiotensin system, one of the main regulators of vascular function, controls
vasoconstriction, inflammation and vascular remodeling. Antagonistic actions of the counter …

Stroke is the 2nd leading cause of death worldwide and the leading cause of physical
disability and cognitive issues. Although we have made progress in certain aspects of stroke …