Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular scaffolds
H Herrmann, U Aebi - Annual review of biochemistry, 2004 - annualreviews.org
▪ Abstract The superfamily of intermediate filament (IF) proteins contains at least 65 distinct
proteins in man, which all assemble into∼ 10 nm wide filaments and are principal structural …
proteins in man, which all assemble into∼ 10 nm wide filaments and are principal structural …
Orchestrating nuclear envelope disassembly and reassembly during mitosis
S Güttinger, E Laurell, U Kutay - Nature reviews Molecular cell biology, 2009 - nature.com
Cell division in eukaryotes requires extensive architectural changes of the nuclear envelope
(NE) to ensure that segregated DNA is finally enclosed in a single cell nucleus in each …
(NE) to ensure that segregated DNA is finally enclosed in a single cell nucleus in each …
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Chromatin, which consists of DNA and associated proteins, contains genetic information and
is a mechanical component of the nucleus. Heterochromatic histone methylation controls …
is a mechanical component of the nucleus. Heterochromatic histone methylation controls …
Transcriptional repression mediated by repositioning of genes to the nuclear lamina
Nuclear compartmentalization seems to have an important role in regulating metazoan
genes,. Although studies on immunoglobulin and other loci have shown a correlation …
genes,. Although studies on immunoglobulin and other loci have shown a correlation …
Nuclear lamins: laminopathies and their role in premature ageing
It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …
Dynamics and interplay of nuclear architecture, genome organization, and gene expression
R Schneider, R Grosschedl - Genes & development, 2007 - genesdev.cshlp.org
The organization of the genome in the nucleus of a eukaryotic cell is fairly complex and
dynamic. Various features of the nuclear architecture, including compartmentalization of …
dynamic. Various features of the nuclear architecture, including compartmentalization of …
Histone H3 variants and their potential role in indexing mammalian genomes: the “H3 barcode hypothesis”
SB Hake, CD Allis - … of the National Academy of Sciences, 2006 - National Acad Sciences
In the history of science, provocative but, at times, controversial ideas have been put forward
to explain basic problems that confront and intrigue the scientific community. These …
to explain basic problems that confront and intrigue the scientific community. These …
The neutrophil nucleus: an important influence on neutrophil migration and function
HR Manley, MC Keightley, GJ Lieschke - Frontiers in immunology, 2018 - frontiersin.org
Neutrophil nuclear morphology has historically been used in haematology for neutrophil
identification and characterisation, but its exact role in neutrophil function has remained …
identification and characterisation, but its exact role in neutrophil function has remained …
Lamin-binding proteins
A-and B-type lamins are the major intermediate filaments of the nucleus. Lamins engage in
a plethora of stable and transient interactions, near the inner nuclear membrane and …
a plethora of stable and transient interactions, near the inner nuclear membrane and …
The heterochromatin protein 1 family
Summary Heterochromatin Protein 1 (HP1) was first discovered in Drosophila as a dominant
suppressor of position-effect variegation and a major component of heterochromatin. The …
suppressor of position-effect variegation and a major component of heterochromatin. The …