[HTML][HTML] Biocatalysis

EL Bell, W Finnigan, SP France, AP Green… - Nature Reviews …, 2021 - nature.com
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …

[HTML][HTML] The Hitchhiker's guide to biocatalysis: recent advances in the use of enzymes in organic synthesis

RA Sheldon, D Brady, ML Bode - Chemical science, 2020 - pubs.rsc.org
Enzymes are excellent catalysts that are increasingly being used in industry and academia.
This perspective is primarily aimed at synthetic organic chemists with limited experience …

Artificial biocatalytic linear cascades for preparation of organic molecules

JH Schrittwieser, S Velikogne, M Hall… - Chemical …, 2018 - ACS Publications
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Broadening the scope of biocatalysis in sustainable organic synthesis

RA Sheldon, D Brady - ChemSusChem, 2019 - Wiley Online Library
This Review is aimed at synthetic organic chemists who may be familiar with organometallic
catalysis but have no experience with biocatalysis, and seeks to provide an answer to the …

The limits to biocatalysis: pushing the envelope

RA Sheldon, D Brady - Chemical communications, 2018 - pubs.rsc.org
In the period 1985 to 1995 applications of biocatalysis, driven by the need for more
sustainable manufacture of chemicals and catalytic,(enantio) selective methods for the …

Recent advances in whole cell biocatalysis techniques bridging from investigative to industrial scale

J Wachtmeister, D Rother - Current opinion in biotechnology, 2016 - Elsevier
Highlights•The use of whole cell biocatalysts is appealing due to their inexpensive
production.•Applications in unconventional media allow high substrate and product …

[HTML][HTML] Biocatalysis with laccases: An updated overview

I Bassanini, EE Ferrandi, S Riva, D Monti - Catalysts, 2020 - mdpi.com
Laccases are multicopper oxidases, which have been widely investigated in recent decades
thanks to their ability to oxidize organic substrates to the corresponding radicals while …

[HTML][HTML] Getting the Most Out of Enzyme Cascades: Strategies to Optimize In Vitro Multi-Enzymatic Reactions

R Siedentop, C Claaßen, D Rother, S Lütz… - Catalysts, 2021 - mdpi.com
In vitro enzyme cascades possess great benefits, such as their synthetic capabilities for
complex molecules, no need for intermediate isolation, and the shift of unfavorable equilibria …

[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

[HTML][HTML] Design and biocatalytic applications of genetically fused multifunctional enzymes

DT Monterrey, I Ayuso-Fernández, I Oroz-Guinea… - Biotechnology …, 2022 - Elsevier
Fusion proteins, understood as those created by joining two or more genes that originally
encoded independent proteins, have numerous applications in biotechnology, from …