Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening
A Santamaria-Martínez, J Epiney, D Srivastava… - Nature …, 2024 - nature.com
The efficacy of anti-cancer therapies depends on the genomic composition of the tumor, its
microenvironment, spatial organization, and intra-tumor heterogeneity. B-cell lymphomas …
microenvironment, spatial organization, and intra-tumor heterogeneity. B-cell lymphomas …
NK Cells in the Lymph Nodes and Their Role in Anti-Tumour Immunity
The lymph nodes are vital to enable adaptive immune responses to infection. Natural killer
(NK) cells are cytotoxic lymphocytes that directly kill cancer cells and modulate the activation …
(NK) cells are cytotoxic lymphocytes that directly kill cancer cells and modulate the activation …
Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target
Follicular lymphoma (FL), the most common indolent non-Hodgkin lymphoma, constitutes a
paradigm of immune tumor microenvironment (TME) contribution to disease onset …
paradigm of immune tumor microenvironment (TME) contribution to disease onset …
Patient-derived lymphomoids preserve the tumor architecture and allow to assess response to therapies in lymphoma
A Santamaria-Martinez, J Epiney, D Srivastava… - bioRxiv, 2024 - biorxiv.org
The efficacy of anti-cancer therapies depends on the genomic composition of the tumor, its
microenvironment, spatial organization, and intra-tumor heterogeneity. B cell lymphomas …
microenvironment, spatial organization, and intra-tumor heterogeneity. B cell lymphomas …
Ex vivo model of breast cancer cell invasion in live lymph node tissue
K Morgaenko, A Arneja, AG Ball, AM Putelo… - …, 2024 - pmc.ncbi.nlm.nih.gov
Lymph nodes (LNs) are common sites of metastatic invasion in breast cancer, often
preceding spread to distant organs and serving as key indicators of clinical disease …
preceding spread to distant organs and serving as key indicators of clinical disease …
Modélisation de la réponse thérapeutique du lymphome folliculaire grâce à un modèle 3D organoïde
N Houmera - 2023 - theses.hal.science
Le lymphome folliculaire (LF) est un lymphome dérivé du centre germinatif (CG), dont les
cellules représentent la contrepartie néoplasique des cellules B du CG. Il est constitué d'une …
cellules représentent la contrepartie néoplasique des cellules B du CG. Il est constitué d'une …