Dissecting the functional role of microRNA 21 in osteosarcoma
Osteosarcoma (OS) is considered to be a malignant bone tumour that mainly affects the long
bones, but it is also involved in other bones of the body. Currently, surgery and …
bones, but it is also involved in other bones of the body. Currently, surgery and …
Biological and clinical relevance of microRNAs in mitochondrial diseases/dysfunctions
Mitochondrial dysfunction arises from an inadequate number of mitochondria, an inability to
provide necessary substrates to mitochondria, or a dysfunction in their electron transport and …
provide necessary substrates to mitochondria, or a dysfunction in their electron transport and …
microRNA-21 promotes breast cancer proliferation and metastasis by targeting LZTFL1
Background Breast cancer is the most common cancer type in female. As microRNAs play
vital role in breast cancer, this study aimed to explore the molecular mechanism and clinical …
vital role in breast cancer, this study aimed to explore the molecular mechanism and clinical …
Arsenic-induced changes in miRNA expression in cancer and other diseases
APF Cardoso, KT Udoh, JC States - Toxicology and applied pharmacology, 2020 - Elsevier
Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …
cellular processes contributing to disease development. Dysregulated miRNA expression …
[HTML][HTML] MicroRNA-21 maintains hematopoietic stem cell homeostasis through sustaining the nuclear factor-B signaling pathway in mice
M Hu, Y Lu, H Zeng, Z Zhang, S Chen, Y Qi, Y Xu… - …, 2021 - ncbi.nlm.nih.gov
Long-term hematopoietic output is dependent on hematopoietic stem cell (HSC)
homeostasis which is maintained by a complex molecular network in which microRNA play …
homeostasis which is maintained by a complex molecular network in which microRNA play …
[HTML][HTML] MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway
B Fan, Y Jin, H Zhang, R Zhao… - International …, 2020 - spandidos-publications.com
Accumulating evidence has demonstrated that microRNAs are associated with malignant
biological behaviour, including tumorigenesis, cancer progression and metastasis via the …
biological behaviour, including tumorigenesis, cancer progression and metastasis via the …
[HTML][HTML] CircPDZD8 promotes gastric cancer progression by regulating CHD9 via sponging miR-197-5p
T Xia, Z Pan, J Zhang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
CircRNAs have been shown to be associated with gastric cancer tumorigenesis. But little
was known about the role of circPDZD8 in gastric cancer. CircPDZD8 was up-regulated in …
was known about the role of circPDZD8 in gastric cancer. CircPDZD8 was up-regulated in …
Impact of bone marrow miR-21 expression on acute myeloid leukemia T lymphocyte fragility and dysfunction
D Moussa Agha, R Rouas, M Najar, F Bouhtit… - Cells, 2020 - mdpi.com
Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy in which
antitumor immunity is impaired. The therapeutic management of AML requires …
antitumor immunity is impaired. The therapeutic management of AML requires …
microRNA expression in acute myeloid leukaemia: New targets for therapy?
D Fletcher, E Brown, J Javadala, P Uysal‐Onganer… - …, 2022 - Wiley Online Library
Recent studies have shown that short non‐coding RNAs, known as microRNAs (miRNAs)
and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia …
and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia …
MicroRNA signature refine response prediction in CML
R Alves, AC Gonçalves, J Jorge, G Marques, D Luís… - Scientific Reports, 2019 - nature.com
Abstract microRNAs (miRs) dysregulation have emerged as a crucial step in tumorigenesis,
being related with cancer development, progression and response to treatment. In chronic …
being related with cancer development, progression and response to treatment. In chronic …