Osteosarcoma (OS) is considered to be a malignant bone tumour that mainly affects the long
bones, but it is also involved in other bones of the body. Currently, surgery and …

Mitochondrial dysfunction arises from an inadequate number of mitochondria, an inability to
provide necessary substrates to mitochondria, or a dysfunction in their electron transport and …

Background Breast cancer is the most common cancer type in female. As microRNAs play
vital role in breast cancer, this study aimed to explore the molecular mechanism and clinical …

Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …

Long-term hematopoietic output is dependent on hematopoietic stem cell (HSC)
homeostasis which is maintained by a complex molecular network in which microRNA play …

Accumulating evidence has demonstrated that microRNAs are associated with malignant
biological behaviour, including tumorigenesis, cancer progression and metastasis via the …

CircRNAs have been shown to be associated with gastric cancer tumorigenesis. But little
was known about the role of circPDZD8 in gastric cancer. CircPDZD8 was up-regulated in …

Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy in which
antitumor immunity is impaired. The therapeutic management of AML requires …

Recent studies have shown that short non‐coding RNAs, known as microRNAs (miRNAs)
and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia …

Abstract microRNAs (miRs) dysregulation have emerged as a crucial step in tumorigenesis,
being related with cancer development, progression and response to treatment. In chronic …