[HTML][HTML] The role of natural antioxidants in cisplatin-induced hepatotoxicity

N Abd Rashid, SAS Abd Halim, SL Teoh… - Biomedicine & …, 2021 - Elsevier
Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug
Administration (FDA) in 1978. Despite its advantages against solid tumors, cisplatin confers …

History, phytochemistry, experimental pharmacology and clinical uses of honey: A comprehensive review with special reference to Unani medicine

S Nikhat, M Fazil - Journal of ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Honey is one of the most popular functional foods,
speculated to be in use since the advent of human civilization. Its health-protective activity is …

Synergistic protective effects of lycopene and N-acetylcysteine against cisplatin-induced hepatorenal toxicity in rats

A Elsayed, A Elkomy, R Elkammar, G Youssef… - Scientific Reports, 2021 - nature.com
Cisplatin (CP) is one of the most frequently used chemotherapy agents. The objective of this
design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine …

7-hydroxycoumarin modulates Nrf2/HO-1 and microRNA-34a/SIRT1 signaling and prevents cisplatin-induced oxidative stress, inflammation, and kidney injury in rats

DH Sami, AS Soliman, AA Khowailed, EHM Hassanein… - Life Sciences, 2022 - Elsevier
The kidneys are vulnerable to toxicity and acute kidney injury (AKI) is the main adverse
effect associated with the clinical use of the chemotherapeutic agent cisplatin (CIS) …

Anti-cancer and protective effects of royal jelly for therapy-induced toxicities in malignancies

Y Miyata, H Sakai - International journal of molecular sciences, 2018 - mdpi.com
Royal jelly (RJ) is a glandular secretion produced by worker honeybees and is a special
food for the queen honeybee. It results in a significant prolongation of the lifespan of the …

[HTML][HTML] Hesperidin ameliorates cisplatin induced hepatotoxicity and attenuates oxidative damage, cell apoptosis, and inflammation in rats

DM Aboraya, A El Baz, EF Risha… - Saudi journal of biological …, 2022 - Elsevier
Cisplatin is one of the most widely used chemotherapeutic anti-cancer drugs that is
associated with multiple systemic toxicities limiting its use. The present study aimed to …

Manuka honey, a unique mono-floral honey. A comprehensive review of its bioactives, metabolism, action mechanisms, and therapeutic merits

FF El-Senduny, NM Hegazi, GE Abd Elghani, MA Farag - Food Bioscience, 2021 - Elsevier
Manuka honey (MH) is a mono-floral honey obtained from the Manuka tree (Leptospermum
scoparium) belonging to the Myrtaceae family and grows as a shrub or a small tree mostly …

Inhibition of myocardial cell apoptosis is important mechanism for ginsenoside in the limitation of myocardial ischemia/reperfusion injury

Z Chen, J Wu, S Li, C Liu, Y Ren - Frontiers in Pharmacology, 2022 - frontiersin.org
Ischemic heart disease has a high mortality, and the recommended therapy is reperfusion.
Nevertheless, the restoration of blood flow to ischemic tissue leads to further damage …

Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

F Taghizadeh, SJ Hosseinimehr… - Pharmacology …, 2021 - Wiley Online Library
Aims Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment,
while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug …

L-carnitine mitigates oxidative stress and disorganization of cytoskeleton intermediate filaments in cisplatin-induced hepato-renal toxicity in rats

A Elkomy, EY Abdelhiee, SE Fadl, MA Emam… - Frontiers in …, 2020 - frontiersin.org
Cisplatin (CP) is one of the most active medications in cancer treatment and has some
adverse effects such as hepatotoxicity and nephrotoxicity. The present research was …