[HTML][HTML] Exosome-based liquid biopsies in cancer: opportunities and challenges

W Yu, J Hurley, D Roberts, SK Chakrabortty… - Annals of …, 2021 - Elsevier
Liquid biopsy in cancer has gained momentum in clinical research and is experiencing a
boom for a variety of applications. There are significant efforts to utilize liquid biopsies in …

Bioactive DNA from extracellular vesicles and particles

EZ Malkin, SV Bratman - Cell death & disease, 2020 - nature.com
Extracellular vesicles (EVs) and particles (EPs) have recently emerged as active carriers of
molecular biomarkers and mediators of intercellular communication. While most …

DNA in extracellular vesicles: biological and clinical aspects

J Elzanowska, C Semira, B Costa‐Silva - Molecular Oncology, 2021 - Wiley Online Library
The study of extracellular vesicles (EVs), especially in the liquid biopsy field, has rapidly
evolved in recent years. However, most EV studies have focused on RNA or protein content …

Circulating and urinary tumour DNA in urothelial carcinoma—Upper tract, lower tract and metastatic disease

KM Rose, HL Huelster, JJ Meeks, BM Faltas… - Nature Reviews …, 2023 - nature.com
Precision medicine has transformed the way urothelial carcinoma is managed. However,
current practices are limited by the availability of tissue samples for genomic profiling and …

Urinary biomarkers in bladder cancer: where do we stand and potential role of extracellular vesicles

MC Oliveira, HR Caires, MJ Oliveira, A Fraga… - Cancers, 2020 - mdpi.com
Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved
in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and …

Exosome, the glass slipper for Cinderella of cancer—bladder cancer?

Y Yang, L Miao, Y Lu, Y Sun, S Wang - Journal of Nanobiotechnology, 2023 - Springer
Exosomes are lipid bilayer vesicles with a diameter of 40–100 nm secreted by almost all
cells. They have been found play crucial regulatory roles in various diseases. With the …

Analytical comparison of methods for extraction of short cell-free DNA from urine

A Oreskovic, ND Brault, N Panpradist, JJ Lai… - The Journal of Molecular …, 2019 - Elsevier
Urine cell-free DNA (cfDNA) is a valuable noninvasive biomarker for cancer mutation
detection, infectious disease diagnosis (eg, tuberculosis), organ transplantation monitoring …

Characteristics and clinical application of extracellular vesicle-derived DNA

JY Hur, KY Lee - Cancers, 2021 - mdpi.com
Simple Summary We reviewed characterization and the role of DNAs derived from
extracellular vesicles focusing on its use for identifying biomarkers. Extracellular vesicles …

Beyond liquid biopsy: Toward non-invasive assays for distanced cancer diagnostics in pandemics

F Ferrara, S Zoupanou, E Primiceri, Z Ali… - Biosensors and …, 2022 - Elsevier
Liquid biopsy technologies have seen a significant improvement in the last decade, offering
the possibility of reliable analysis and diagnosis from several biological fluids. The use of …

[HTML][HTML] Extracellular vesicles as a promising biomarker resource in liquid biopsy for cancer

T Tamura, Y Yoshioka, S Sakamoto… - Extracellular …, 2021 - pmc.ncbi.nlm.nih.gov
Liquid biopsy is a minimally invasive biopsy method that uses molecules in body fluids as
biomarkers, and it has attracted attention as a new cancer therapy tool. Liquid biopsy has …