Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery

M Shringarpure, S Gharat, M Momin… - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Epilepsy, a major neurological disorder affects about 1% of the Indian
population. The discovery of noninvasive strategies for epilepsy presents a challenge for the …

Nanovesicular-mediated intranasal drug therapy for neurodegenerative disease

S Singh, R Shukla - AAPS PharmSciTech, 2023 - Springer
Numerous neurodegenerative conditions, such as Alzheimer's, Huntington's, Parkinson's,
amyotrophic lateral sclerosis, and glioblastoma multiform are now becoming significant …

Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications

Simrah, A Hafeez, SA Usmani, MP Izhar - … -Schmiedeberg's Archives of …, 2024 - Springer
The application of nanotechnology with integration of chemical sciences is increasing
continuously in the management of diseases. The drug's physicochemical and …

Superparamagnetic iron oxide–loaded lipid nanocarriers incorporated in thermosensitive in situ gel for magnetic brain targeting of clonazepam

H Abbas, H Refai, N El Sayed - Journal of pharmaceutical sciences, 2018 - Elsevier
The objective of the study was to target clonazepam to the brain through the intranasal
olfactory mucosa using nanolipid carriers loaded with superparamagnetic iron oxide …

Dysfunction of ABC transporters at the surface of BBB: potential implications in intractable epilepsy and applications of nanotechnology enabled drug delivery

R Mohi-ud-Din, RH Mir, PA Mir, N Banday… - Current Drug …, 2022 - ingentaconnect.com
Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …

Nose-to-brain drug delivery for the treatment of CNS disease: New development and strategies

L Du, L Chen, F Liu, W Wang, H Huang - International Review of …, 2023 - Elsevier
Delivering drugs to the brain has always been a challenging task due to the restrictive
properties of the blood-brain barrier (BBB). Intranasal delivery is therefore emerging as an …

Lipid nanocapsules: A novel strategy for brain targeting via nasal administration

M IBRAHIM, E BASALIOUS, M El-NABARAWI… - 2024 - repository.msa.edu.eg
In spite of the great advance in drug delivery systems (DDSs) for the control of the
neurological disorders like Alzheimer's disease, Parkinson's disease, epilepsy and seizures …

Vesicular carriers for direct nose-to-brain drug delivery

PK Deshmukh, SN Jain, PO Patil… - Direct Nose-to-Brain Drug …, 2021 - Elsevier
The nasal route of administration is gaining a lot of interest these days in order to achieve
the efficient brain targeting. The superior therapeutic outcomes of nasal delivery are due to …

Phospholipid-Based Nanoplatforms: Evolving as Promising Carriers for Therapeutic Intervention

A Chakraborty, P Dhar - Handbook of Nanotechnology in …, 2022 - taylorfrancis.com
For the last few decades, nanocarrier strategies have endeavored to cause a revolution in
the diagnostic and therapeutic domain due to the miniature dimensions of nanoparticles …

[PDF][PDF] DEVELOPMENT, OPTIMIZATION AND EVALUATION OF PSORALEN LOADED TRANSFERSOMAL GEL FOR TREATMENT OF PSORIASIS

SS Dongare, VP Bhogale - 2024 - wjpr.s3.ap-south-1.amazonaws.com
Background: Psoriasis is a chronic autoimmune inflammatory disorder characterized by
thickened inflamed skin lesions covered with scaly patches. Psoralen is a phytoconstituent …