Application of ToxCast/Tox21 data for toxicity mechanism-based evaluation and prioritization of environmental chemicals: Perspective and limitations
In response to the need to minimize the use of experimental animals, new approach
methodologies (NAMs) using advanced technology have emerged in the 21st century …
methodologies (NAMs) using advanced technology have emerged in the 21st century …
The dichloroacetamide safener benoxacor is enantioselectively metabolized by monkey liver microsomes and cytosol
D Simonsen, J Heffelfinger, DM Cwiertny… - Environmental toxicology …, 2022 - Elsevier
The metabolism and toxicity of current-use herbicide safeners remain understudied. We
investigated the enantioselective metabolism of the safener benoxacor in Rhesus monkey …
investigated the enantioselective metabolism of the safener benoxacor in Rhesus monkey …
Benoxacor is enantioselectively metabolized by microsomes and cytosol from the human liver
D Simonsen, J Heffelfinger, DM Cwiertny… - Emerging …, 2023 - Elsevier
Benoxacor is a safener added to current-use herbicide formulations to protect the target crop
from herbicidal toxicity. It is an emerging environmental contaminant that has been detected …
from herbicidal toxicity. It is an emerging environmental contaminant that has been detected …
Disposition and Toxicity of 2, 2', 5, 5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure
The disposition and toxicity of lower chlorinated PCBs (LC-PCBs) with less than five chlorine
substituents have received little attention to date. This study characterizes the distribution of …
substituents have received little attention to date. This study characterizes the distribution of …