How RNases shape mitochondrial transcriptomes

J Cartalas, L Coudray, A Gobert - International Journal of Molecular …, 2022 - mdpi.com
Mitochondria are the power houses of eukaryote cells. These endosymbiotic organelles of
prokaryote origin are considered as semi-autonomous since they have retained a genome …

Importance of residue 248 in Escherichia coli RNase P RNA mediated cleavage

G Mao, AS Srivastava, S Wu, D Kosek, LA Kirsebom - Scientific Reports, 2023 - nature.com
Abstract tRNA genes are transcribed as precursors and RNase P generates the matured
5'end of tRNAs. It has been suggested that residue− 1 (the residue immediately 5ʹ of the …

RNase P: Beyond Precursor tRNA Processing

P Wang, J Lin, X Zheng, X Xu - Genomics, Proteomics & …, 2024 - academic.oup.com
Abstract Ribonuclease P (RNase P) was first described in the 1970's as an
endoribonuclease acting in the maturation of precursor transfer RNAs (tRNAs). More recent …

Protein-only RNase P function in Escherichia coli: viability, processing defects and differences between PRORP isoenzymes

M Gößringer, M Lechner, N Brillante… - Nucleic Acids …, 2017 - academic.oup.com
The RNase P family comprises structurally diverse endoribonucleases ranging from
complex ribonucleoproteins to single polypeptides. We show that the organellar (At …

Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P

BP Klemm, A Karasik, KJ Kaitany, A Shanmuganathan… - Rna, 2017 - rnajournal.cshlp.org
Protein-only ribonuclease P (PRORP) is an enzyme responsible for catalyzing the 5′ end
maturation of precursor transfer ribonucleic acids (pre-tRNAs) encoded by various cellular …

Determination of protein‐only RNase P interactome in Arabidopsis mitochondria and chloroplasts identifies a complex between PRORP1 and another NYN domain …

A Bouchoucha, F Waltz, G Bonnard, M Arrivé… - The Plant …, 2019 - Wiley Online Library
The essential type of endonuclease that removes 5′ leader sequences from transfer RNA
precursors is called RNase P. While ribonucleoprotein RNase P enzymes containing a …

Synthetic riboswitches for the analysis of tRNA processing by eukaryotic RNase P enzymes

A Ender, N Grafl, T Kolberg, S Findeiß, PF Stadler… - RNA, 2022 - rnajournal.cshlp.org
Removal of the 5′-leader region is an essential step in the maturation of tRNA molecules in
all domains of life. This reaction is catalyzed by various RNase P activities, ranging from …

A minimal RNA substrate with dual fluorescent probes enables rapid kinetics and provides insight into bacterial RNase P active site interactions

T Huang, A Chamberlain, J Zhu, ME Harris - RSC Chemical Biology, 2024 - pubs.rsc.org
Bacterial ribonuclease P (RNase P) is a tRNA processing endonuclease that occurs
primarily as a ribonucleoprotein with a catalytic RNA subunit (P RNA). As one of the first …

[图书][B] Production and investigation of highly thermophilic multi-domain carbohydrate-active enzymes

D Krska - 2021 - search.proquest.com
With the looming threat of climate change caused largely by an excess of carbon dioxide in
the atmosphere, recent scientific efforts have focused on the substitution of fossil fuels and …

[图书][B] Investigating the mechanics of N4BP1 in mammalian cells

Z Brown - 2021 - search.proquest.com
The bulk of mRNA turnover proceeds through a deadenylation dependent mechanism,
whereby mRNAs have their 3'-poly (A) tails trimmed, followed by either degradation by the 3' …