This review rigorously assesses the burgeoning research into the role of polyphenols in
modulating mitophagy, an essential cellular mechanism for the targeted removal of impaired …

Neurodegenerative diseases (NDs) are characterized by progressive and irreversible
neuronal loss, accompanied by a range of pathological pathways, including aberrant protein …

The organophosphorus insecticide Chlorpyrifos (CPF) is widely used worldwide due to its
high effectiveness. However, when ingested through the mouth and nose, it can cause …

Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS), Huntington disease (HD), and Multiple sclerosis (MS) …

Autophagy regulates intermittent hypoxia (IH)-induced obstructive sleep apnea–hypopnea
syndrome (OSAHS). We investigated the effects of IH and its withdrawal on cognitive …

Plant secondary metabolites (PSMs) are a diverse group of bioactive compounds, including
flavonoids, polyphenols, saponins, and terpenoids, which have been recognised for their …

Spinocerebellar ataxia type 3 (SCA3), caused by the abnormal expansion of polyglutamine
(polyQ) in the ataxin-3 protein, is one of the inherited polyQ neurodegenerative diseases …

Polyphenols are the most prevalent naturally occurring phytochemicals in the human diet
and range in complexity from simple molecules to high-molecular-weight polymers. They …

Autophagy, a vital cell process, has garnered attention for its role in various diseases and
potential therapeutic interventions. Dysregulation of autophagy contributes to conditions …

Basic research on chronic rhinosinusitis (CRS) has advanced significantly in the past two
decades, yet a comprehensive understanding of its pathogenic mechanisms remains …