Antibacterial activities with the structure-activity relationship of coumarin derivatives

HL Qin, ZW Zhang, L Ravindar, KP Rakesh - European journal of medicinal …, 2020 - Elsevier
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

WY Fang, L Ravindar, KP Rakesh… - European Journal of …, 2019 - Elsevier
At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …

An overview of quinazolines: Pharmacological significance and recent developments

V Alagarsamy, K Chitra, G Saravanan… - European journal of …, 2018 - Elsevier
Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

Synthesis and antioxidant activities of Schiff bases and their complexes: a review

W Al Zoubi, AAS Al‐Hamdani… - Applied Organometallic …, 2016 - Wiley Online Library
Schiff bases, named after Hugo Schiff, are aldehyde‐or ketone‐like compounds in which the
carbonyl group is replaced by imine or azomethine group. They are widely used for …

Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA)

HL Qin, J Liu, WY Fang, L Ravindar… - European journal of …, 2020 - Elsevier
Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Laccase catalysis for the synthesis of bioactive compounds

T Kudanga, B Nemadziva, M Le Roes-Hill - Applied Microbiology and …, 2017 - Springer
The demand for compounds of therapeutic value is increasing mainly because of new
applications of bioactive compounds in medicine, pharmaceutical, agricultural, and food …

Pyridine- and Thiazole-Based Hydrazides with Promising Anti-inflammatory and Antimicrobial Activities along with Their In Silico Studies

V Kamat, R Santosh, B Poojary, SP Nayak… - ACS …, 2020 - ACS Publications
A new class of compounds formed by the linkage of− C (O)–NH–with pyridine and thiazole
moieties was designed, synthesized, and characterized by various spectral approaches. The …

Schiff base metal complexes as anti-inflammatory agents

QUA Sandhu, M Pervaiz, A Majid… - Journal of …, 2023 - Taylor & Francis
Schiff bases (SB) have unique potential to bind metal ions for widespread applications,
especially in the pharmacological industry. The condensation of primary imine and carbonyl …

Synthesis, characterization, and determination antioxidant activities for new Schiff base complexes derived from 2-(1H-indol-3-yl)-ethylamine and metal ion complexes

MJ Kareem, AAS Al-Hamdani, YG Ko… - Journal of molecular …, 2021 - Elsevier
Tetradentate bidentate Schiff base (L 1) from 4-amino-1.5-dimethyl-2-phenyl-1.2-dihydro-
pyrazol-3-one and 2-(1H-indol-3-yl)-ethylamine and benzene-1.4-dicarbaldehyde was …

Triazole derivatives as potential antifungal agents: A structure-activity relationship (SAR) studies

Y Hu, Z Liu, G Zha, S Long, MB Sridhara… - Process …, 2023 - Elsevier
Today's research is focused on developing new safe drugs of clinical importance. Nitrogen-
containing heterocycles are abundant in the common of therapeutic scaffolds. Triazoles are …