A review on multivariate curve resolution applied to spectroscopic and chromatographic data acquired during the real-time monitoring of evolving multi-component …

SJ Mazivila, JLM Santos - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
This review addresses the most important results arising from the combination of multivariate
curve resolution− alternating least-squares (MCR-ALS) with both spectroscopic and …

MCR-ALS GUI 2.0: New features and applications

J Jaumot, A de Juan, R Tauler - Chemometrics and Intelligent Laboratory …, 2015 - Elsevier
An updated version of the graphical user-friendly interface related to the Multivariate Curve
Resolution-Alternating Least Squares (MCR-ALS) algorithm is presented. This GUI works …

Current applications of Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) in pharmaceutical analysis

MA Mansouri, M Kharbach, A Bouklouze - Journal of Pharmaceutical …, 2023 - Elsevier
The present review encompasses various applications of multivariate curve resolution-
alternating least squares (MCR-ALS) as a promising data handling, which is issued by …

Fabrication of dual functional 3D-flower shaped NaYF4: Dy3+/Eu3+ and graphene oxide based NaYF4: Dy3+/Eu3+ nanocomposite material as a potable …

R Singhaal, NA Ashashi, C Sen, S Devi… - Nano-Structures & Nano …, 2023 - Elsevier
The existence of improper pharmaceutical contaminants in water bodies has endangered
the environment and human health worldwide, which makes it ineludible to develop …

Efficient kinetic data acquisition and model prediction: continuous flow microreactors, inline fourier transform infrared spectroscopy, and self-modeling curve resolution

V Fath, P Lau, C Greve, N Kockmann… - … Process Research & …, 2020 - ACS Publications
This work presents and evaluates an approach to obtain and model kinetic data by
combining a microreactor setup and real-time reaction monitoring through inline Fourier …

Photostability and ex-vivo permeation studies on diclofenac in topical niosomal formulations

G Ioele, L Tavano, M De Luca, G Ragno, N Picci… - International journal of …, 2015 - Elsevier
Photostability studies were performed on topical formulations containing diclofenac (DC).
Niosomal gels were designed as photostabilization systems and ascorbic acid was also …

Multivariate curve resolution of incomplete fused multiset data from chromatographic and spectrophotometric analyses for drug photostability studies

M De Luca, G Ragno, G Ioele, R Tauler - Analytica Chimica Acta, 2014 - Elsevier
An advanced and powerful chemometric approach is proposed for the analysis of
incomplete multiset data obtained by fusion of hyphenated liquid chromatographic DAD/MS …

Comprehensive modeling of bloodstain aging by multivariate Raman spectral resolution with kinetics

A Takamura, D Watanabe, R Shimada… - Communications …, 2019 - nature.com
Blood, as a cardinal biological system, is a challenging target for biochemical
characterization because of sample complexity and a lack of analytical approaches. To …

Multivariate process trajectories: capture, resolution and analysis

A Bogomolov - Chemometrics and Intelligent Laboratory Systems, 2011 - Elsevier
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Powerful combination of analytical and chemometric methods for the photodegradation of 5-Fluorouracil

C Gómez-Canela, G Bolivar-Subirats, R Tauler… - … of Pharmaceutical and …, 2017 - Elsevier
The photodegradation of the antineoplastic drug 5-fluorouracil (5-FU) under the action of UV
light was studied using UV–vis spectroscopy and High Performance Liquid Chromatography …