Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
Cannabidiol (CBD) in cancer management
K O'Brien - Cancers, 2022 - mdpi.com
Simple Summary Cannabidiol (CBD) is one of the main constituents of the plant Cannabis
sativa. Surveys suggest that medicinal cannabis is popular amongst people diagnosed with …
sativa. Surveys suggest that medicinal cannabis is popular amongst people diagnosed with …
[HTML][HTML] Inverted U-shaped dose-response curve of the anxiolytic effect of cannabidiol during public speaking in real life
AW Zuardi, NP Rodrigues, AL Silva… - Frontiers in …, 2017 - frontiersin.org
The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol
(CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve …
(CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve …
[HTML][HTML] Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test
IM Linares, AW Zuardi, LC Pereira… - Brazilian Journal of …, 2018 - SciELO Brasil
Objective: Cannabidiol (CBD), one of the non-psychotomimetic compounds of Cannabis
sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response …
sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response …
Pharmacokinetic and behavioural profile of THC, CBD, and THC+ CBD combination after pulmonary, oral, and subcutaneous administration in rats and confirmation of …
T Hložek, L Uttl, L Kadeřábek, M Balíková… - European …, 2017 - Elsevier
Metabolic and behavioural effects of, and interactions between Δ9-tetrahydrocannabinol
(THC) and cannabidiol (CBD) are influenced by dose and administration route. Therefore …
(THC) and cannabidiol (CBD) are influenced by dose and administration route. Therefore …
Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders
Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …
Cannabidiol reduces ethanol consumption, motivation and relapse in mice
A Viudez‐Martínez, MS García‐Gutiérrez… - Addiction …, 2018 - Wiley Online Library
This study evaluated the effects of cannabidiol (CBD) on ethanol reinforcement, motivation
and relapse in C57BL/6 J mice. The effects of CBD (60 mg/kg, ip) on blood ethanol …
and relapse in C57BL/6 J mice. The effects of CBD (60 mg/kg, ip) on blood ethanol …
Cannabidiol as a potential new type of an antipsychotic. A critical review of the evidence
C Rohleder, JK Müller, B Lange… - Frontiers in …, 2016 - frontiersin.org
There is urgent need for the development of mechanistically different and less side-effect
prone antipsychotic compounds. The endocannabinoid system has been suggested to …
prone antipsychotic compounds. The endocannabinoid system has been suggested to …
Role of the endocannabinoid system in the pathophysiology of schizophrenia
M Fakhoury - Molecular neurobiology, 2017 - Springer
The endocannabinoid system (ECS) is a group of neuromodulatory lipids, enzymes, and
receptors involved in numerous behavioral and physiological processes such as mood …
receptors involved in numerous behavioral and physiological processes such as mood …
Cannabidiol prevents motor and cognitive impairments induced by reserpine in rats
FF Peres, R Levin, MA Suiama, MC Diana… - Frontiers in …, 2016 - frontiersin.org
Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents
antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's …
antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's …