Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Galectins are a family of carbohydrate-binding lectins modulating cell events such as cell
proliferation, apoptosis, adhesion or migration by cross-linking the glycan structures of cell …

Discovery of glycan‐competitive galectin‐3‐binding compounds that attenuate lung fibrosis
in a murine model and that block intracellular galectin‐3 accumulation at damaged vesicles …

Symmetrical and asymmetrical fluorinated phenyltriazolyl-thiodigalactoside derivatives have
been synthesized and evaluated as inhibitors of galectin-1 and galectin-3. Systematic tuning …

The Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has been rapidly
transmitting and leaving its footprints across the globe. Stringent measures like complete …

Breast cancer has the highest incidence and mortality in females, while prostate cancer has
the second-highest incidence in males. Studies have shown that compounds from Brazilian …

Abstract Galectin-3 (gal-3), a member of the galectin family, is a glycoprotein with high
affinity for β-galactoside. Gal-3 is a cytoplasmically synthesized protein that can shuttle …

Galectin inhibitors are urgently needed to understand the mode of action and druggability of
different galectins, but potent and selective agents still evade researchers. Small-sized …

Carbohydrates, traditionally known for their energy-providing role, have gained significant
attention in drug discovery due to their diverse bioactivities and stereodiversity. However …

In this work, we present a bottom-up approach for the synthesis of lactose-functionalized
glycomacromolecules and glycofunctionalized liposomes and apply these compounds to …