PrEP rollout in Africa: status and opportunity

EM Irungu, JM Baeten - Nature medicine, 2020 - nature.com
Following recommendations by the World Health Organization in 2015, and key clinical
trials, countries in sub-Saharan Africa, the region with the highest burden of human …

The case for an HIV cure and how to get there

M Dybul, T Attoye, S Baptiste, P Cherutich, F Dabis… - The Lancet …, 2021 - thelancet.com
In light of the increasing global burden of new HIV infections, growing financial
requirements, and shifting funding landscape, the global health community must accelerate …

PrEP uptake, persistence, adherence, and effect of retrospective drug level feedback on PrEP adherence among young women in southern Africa: Results from HPTN …

C Celum, S Hosek, M Tsholwana, S Kassim… - PLoS …, 2021 - journals.plos.org
Background Pre-exposure prophylaxis (PrEP) is highly effective and an important prevention
tool for African adolescent girls and young women (AGYW), but adherence and persistence …

[HTML][HTML] Sexually transmitted infections treatment guidelines, 2021

KA Workowski - MMWR. Recommendations and Reports, 2021 - cdc.gov
These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

PrEP use and HIV seroconversion rates in adolescent girls and young women from Kenya and South Africa: the POWER demonstration project

CL Celum, EA Bukusi, LG Bekker… - Journal of the …, 2022 - Wiley Online Library
Introduction HIV incidence remains high among African adolescent girls and young women
(AGYW). The primary objective of this study is to assess pre‐exposure prophylaxis (PrEP) …

Integrating preexposure prophylaxis delivery in routine family planning clinics: a feasibility programmatic evaluation in Kenya

KK Mugwanya, J Pintye, J Kinuthia, F Abuna… - PLoS …, 2019 - journals.plos.org
Background Young women account for a disproportionate fraction of new HIV infections in
Africa and are a priority population for HIV prevention, including implementation of …

Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study

A Nel, N Van Niekerk, B Van Baelen, M Malherbe… - The Lancet …, 2021 - thelancet.com
Summary Background The Ring Study, a phase 3 trial in 1959 sexually active women
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …

Preferences for long‐acting Pre‐Exposure prophylaxis (PreP) for HIV prevention among South African youth: results of a discrete choice experiment

AM Minnis, M Atujuna, EN Browne… - African Journal of …, 2020 - journals.lww.com
Introduction: Existing biomedical HIV prevention options, though highly effective, present
substantial adherence challenges. End-user input on early-stage design of new HIV …

[图书][B] Guidelines on long-acting injectable cabotegravir for HIV prevention

World Health Organization - 2022 - books.google.com
In this guideline, WHO recommends that long-acting injectable cabotegravir (CAB-LA) may
be offered as an additional HIV prevention option for people at substantial risk of HIV …

The current landscape of pre-exposure prophylaxis service delivery models for HIV prevention: a scoping review

J Vanhamel, A Rotsaert, T Reyniers… - BMC Health Services …, 2020 - Springer
Background Strengthening HIV prevention is imperative given the continued high HIV
incidence worldwide. The introduction of oral PrEP as a new biomedical HIV prevention tool …