[HTML][HTML] Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Fungal infections in HIV/AIDS

AH Limper, A Adenis, T Le… - The Lancet Infectious …, 2017 - thelancet.com
Fungi are major contributors to the opportunistic infections that affect patients with HIV/AIDS.
Systemic infections are mainly with Pneumocystis jirovecii (pneumocystosis), Cryptococcus …

[HTML][HTML] Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

JN Jarvis, DS Lawrence, DB Meya… - … England Journal of …, 2022 - Mass Medical Soc
Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …

[图书][B] Textbook of medical mycology

J Chander - 2017 - books.google.com
Medical mycology refers to the study of fungi that produce disease in humans and other
animals, and of the diseases they produce, their ecology, and their epidemiology. This new …

Cryptococcosis

EK Maziarz, JR Perfect - Infectious disease clinics, 2016 - id.theclinics.com
Cryptococcosis is an infectious disease with worldwide distribution and wide array of clinical
presentations caused by pathogenic encapsulated yeasts in the genus Cryptococcus …

[HTML][HTML] Antifungal combinations for treatment of cryptococcal meningitis in Africa

SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …

Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy

PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Molecular evolution of antifungal drug resistance

N Robbins, T Caplan, LE Cowen - Annual review of …, 2017 - annualreviews.org
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …

Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

[HTML][HTML] Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients

R Bellmann, P Smuszkiewicz - Infection, 2017 - Springer
Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …