Oxidative stress and inflammation interact in the development of diabetic atherosclerosis.
Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species …

Haemodynamic forces influence the functional properties of vascular endothelium.
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …

Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Microvascular dysfunction leads to multi-organ failure and mortality in sepsis. Our previous
studies demonstrated that administration of exogenous endothelial progenitor cells (EPCs) …

Background and Purpose—Blood-brain barrier (BBB) disruption is a critical pathological
feature after stroke. MicroRNA-126 (miR-126) maintains BBB integrity by regulating …

Diabetes mellitus, together with its complications, has been increasing in prevalence
worldwide. Its complications include cardiovascular disease (eg, myocardial infarction …

After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …

Mesenchymal stem cells (MSC s) have been considered as an attractive tool for the therapy
of diseases. Accumulating evidence indicates that the healing effects of MSC s are mainly …