Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is
classed into three subfamilies based on their structural and activation characteristics …

Alzheimer's disease (AD) is an irreversible and progressive brain disorder that slowly
destroys memory and thinking skills, and, eventually, the ability to perform simple tasks. As …

Because disease-associated microglia (DAM) and disease-associated astrocytes (DAA) are
involved in the pathophysiology of Alzheimer's disease (AD), we systematically identified …

Several genetic variants of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2)
have been shown to increase the risk of developing Alzheimer's disease (AD) supporting a …

Amyloid beta (Aβ)-mediated synapse dysfunction is an early event in Alzheimer's disease
(AD) pathogenesis and previous studies suggest that NMDA receptor (NMDAR) …

Alzheimer's disease (AD) is a complex disease involved oxidative stress and inflammation in
its pathogenesis. Acetyl-11-keto-β-boswellic acid (AKBA) is an active triterpenoid compound …

Relevance-based selectivity and high energy cost are two distinct features of long-term
memory (LTM) formation that warrant its default inhibition. Spaced repetition of learning is a …

Lysine specific demethylase 1 (LSD1) is a key epigenetic eraser enzyme implicated in
cancer metastases and recurrence. Nuclear LSD1 phosphorylated at serine 111 (nLSD1p) …

Alzheimer's disease (AD) is a neurodegenerative disorder, marked by cortical and
hippocampal deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles and cognitive …

Conversion of astroglia into functional neurons has been considered a promising
therapeutic strategy for neurodegenerative diseases. Recent studies reported that …