Toxoplasma gondii is known to infect a considerable number of mammalian and avian
species and a substantial proportion of the world's human population. The parasite has an …

Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells,
in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient …

The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of
malarial effector proteins across a parasite-encasing vacuolar membrane into host …

Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …

Toxoplasma gondii is a parasitic protist infecting a wide group of warm-blooded animals,
ranging from birds to humans. While this infection is usually asymptomatic in healthy …

For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

Intraerythrocytic malaria parasites reside within a parasitophorous vacuolar membrane
(PVM) generated during host cell invasion. Erythrocyte remodelling and parasite metabolism …

Macrophages play an essential role in the early immune response against Toxoplasma and
are the cell type preferentially infected by the parasite in vivo. Interferon gamma (IFNγ) elicits …

Rhoptries are specialized secretory organelles found in the Apicomplexa phylum, playing a
central role in the establishment of parasitism. The rhoptry content includes membranous as …