Iron overload in alcoholic liver disease: underlying mechanisms, detrimental effects, and potential therapeutic targets
LX Li, FF Guo, H Liu, T Zeng - Cellular and Molecular Life Sciences, 2022 - Springer
Alcoholic liver disease (ALD) is a global public health challenge due to the high incidence
and lack of effective therapeutics. Evidence from animal studies and ALD patients has …
and lack of effective therapeutics. Evidence from animal studies and ALD patients has …
Atherogenesis and iron: from epidemiology to cellular level
F Vinchi, MU Muckenthaler, MC Da Silva… - Frontiers in …, 2014 - frontiersin.org
Iron accumulates in human atherosclerotic lesions but whether it is a cause or simply a
downstream consequence of the atheroma formation has been an open question for …
downstream consequence of the atheroma formation has been an open question for …
[HTML][HTML] Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats
MO de Souza, M Silva, ME Silva, R de Paula Oliveira… - Nutrition, 2010 - Elsevier
OBJECTIVE: We investigated the antioxidant potential and hypocholesterolemic effects of
acai (Euterpe oleracea Mart.) pulp ingestion in rats fed a standard or hypercholesterolemic …
acai (Euterpe oleracea Mart.) pulp ingestion in rats fed a standard or hypercholesterolemic …
Iron metabolism in nonalcoholic fatty liver disease
JE Nelson, H Klintworth, KV Kowdley - Current gastroenterology reports, 2012 - Springer
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) is a common worldwide clinical and
major public health problem affecting both adults and children in developed nations …
major public health problem affecting both adults and children in developed nations …
The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease
M Mouzaki, JP Allard - Journal of clinical gastroenterology, 2012 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in
adults and children and is currently the third most common indication for liver transplantation …
adults and children and is currently the third most common indication for liver transplantation …
Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury
TCH Tan, DHG Crawford, LA Jaskowski… - Laboratory …, 2013 - nature.com
Endoplasmic reticulum (ER) stress is an important pathogenic mechanism for alcoholic
(ALD) and nonalcoholic fatty liver disease (NAFLD). Iron overload is an important cofactor …
(ALD) and nonalcoholic fatty liver disease (NAFLD). Iron overload is an important cofactor …
Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats
Y Minamiyama, S Takemura, S Kodai… - American Journal …, 2010 - journals.physiology.org
Accumulating evidence suggests that alcohol, hepatitis C virus infection, steatosis with
obesity, and insulin resistance are accompanied by iron overload states. Phlebotomy and …
obesity, and insulin resistance are accompanied by iron overload states. Phlebotomy and …
Effects of excess dietary iron and fat on glucose and lipid metabolism
JS Choi, IU Koh, HJ Lee, WH Kim, J Song - The Journal of nutritional …, 2013 - Elsevier
Purpose Diets rich in fat and energy are associated with metabolic syndrome (MS).
Increased body iron stores have been recognized as a feature of MS. High-fat diets (HFs) …
Increased body iron stores have been recognized as a feature of MS. High-fat diets (HFs) …
[PDF][PDF] Hepatic iron loading in mice increases cholesterol biosynthesis
RM Graham, ACG Chua, KW Carter, RD Delima… - …, 2010 - Wiley Online Library
Iron and cholesterol are both essential metabolites in mammalian systems, and too much or
too little of either can have serious clinical consequences. In addition, both have been …
too little of either can have serious clinical consequences. In addition, both have been …
Non-transferrin-bound iron in the spotlight: novel mechanistic insights into the vasculotoxic and atherosclerotic effect of iron
F Vinchi - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: While atherosclerosis is an almost inevitable consequence of aging, food
preferences, lack of exercise, and other aspects of the lifestyle in many countries, the …
preferences, lack of exercise, and other aspects of the lifestyle in many countries, the …