Pathological angiogenesis: mechanisms and therapeutic strategies

AC Dudley, AW Griffioen - Angiogenesis, 2023 - Springer
In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

[HTML][HTML] Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis …

SC Tao, T Yuan, BY Rui, ZZ Zhu, SC Guo… - Theranostics, 2017 - ncbi.nlm.nih.gov
An excess of glucocorticoids (GCs) is reported to be one of the most common causes of
osteonecrosis of the femoral head (ONFH). In addition, GCs can induce bone cell apoptosis …

Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action

CH Storch, PH Hoeger - British Journal of Dermatology, 2010 - academic.oup.com
Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

Diagnosis and management of infantile hemangioma

DH Darrow, AK Greene, AJ Mancini, AJ Nopper… - …, 2015 - publications.aap.org
Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors,
they have the unique ability to involute after proliferation, often leading primary care …

Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial

Y Ji, S Chen, J Zhou, K Yang, X Zhang… - Blood, The Journal …, 2022 - ashpublications.org
Abstract The Kasabach-Merritt phenomenon (KMP) in kaposiform hemangioendothelioma
(KHE) is characterized by life-threatening thrombocytopenia and consumptive coagulopathy …

Infantile hemangiomas: an update on pathogenesis and therapy

TS Chen, LF Eichenfield, SF Friedlander - Pediatrics, 2013 - publications.aap.org
Infantile hemangiomas (IHs) are the most common vascular tumors of childhood, affecting∼
5% of all infants. Although most lesions proliferate and then involute with minimal …

Non–beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

CT Seebauer, MS Graus, L Huang… - The Journal of …, 2022 - Am Soc Clin Investig
Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are
composed of R (+) and S (–) enantiomers: the R (+) enantiomer is largely devoid of beta …

Pathogenesis of infantile haemangioma

S Greenberger, J Bischoff - British Journal of Dermatology, 2013 - academic.oup.com
Haemangioma is a vascular tumour of infancy that is well known for its rapid growth during
the first weeks to months of a child's life, followed by a spontaneous but slow involution …

Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: a multicenter retrospective study

Y Ji, S Chen, B Xiang, K Li, Z Xu, W Yao… - … Journal of Cancer, 2017 - Wiley Online Library
Kaposiform hemangioendothelioma (KHE) is an aggressive disease with high morbidity and
mortality. The aim of this study was to retrospectively evaluate the efficacy and safety of …