Acetylcoumarin in cyclic and heterocyclic-containing coumarins: Synthesis and biological applications

NH Nasab, F Azimian, HG Kruger, SJ Kim - Tetrahedron, 2022 - Elsevier
In design and development of bioactive compounds, coumarins as ubiquitous natural
heterocyclic compounds have been widely used. In particular, the combination of the …

Insights into the chemistry and therapeutic potential of acrylonitrile derivatives

O Unsal Tan, M Zengin - Archiv der Pharmazie, 2022 - Wiley Online Library
Acrylonitrile is a fascinating scaffold widely found in many natural products, drugs, and drug
candidates with various biological activities. Several drug molecules such as entacapone …

[HTML][HTML] Targeting the Cyclin-Dependent Kinase Family in Anticancer Drug Discovery: From Computational to Experimental Studies

P Solanki, S Sarwadia, M Athar, PC Jha… - Chemical Physics …, 2024 - Elsevier
Uncontrolled cell proliferation, primarily regulated by cyclin-dependent kinases (CDKs), is a
critical driver of cancer progression, with dysregulation of CDKs contributing to various …

In vitro study of redox properties of azolyl-lactones in human serum

M Simić, J Kotur-Stevuljević, P Jovanović… - Journal of the Serbian …, 2023 - shd-pub.org.rs
Disruption of the redox balance in the body causes oxidative stress that can initiate many
diseases. While antioxidants reduce the level of oxidizing compounds in the medium …

New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents

AM Semenova, YR Gadzhiakhmedova… - Russian Journal of …, 2022 - Springer
Amino-3-(cyanomethyl)-1 H-pyrazole-4-carbonitrile enters into condensation reactions with
β-diketones and dibenzalacetone to form 2-(cyanomethyl) pyrazolo [1, 5-a] pyrimidine-3 …

[PDF][PDF] This is an early electronic version of an as-received manuscript that has been

JD Petrović - pdfs.semanticscholar.org
revised 24 January 2020; accepted 29 January 2020) Abstract: This manuscript presents the
fast determination of the volatile components of widely used culinary herbs and spices …