The complexities of modern biomedicine are rapidly increasing. Thus, modeling and
simulation have become increasingly important as a strategy to understand and predict the …

The use of finite element models as research tools in biomechanics and orthopedics has
grown exponentially over the last 20 years. However, the attention to mesh quality, model …

Finite element has been used for more than four decades to study and evaluate the
mechanical behaviour total joint replacements. In Huiskes seminal paper “Failed innovation …

Background Musculoskeletal soft tissues, such as articular cartilage, ligaments, knee
meniscus and intervertebral disk, have a complex structure, which provides elasticity and …

In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …

Finite element (FE) analysis has been applied for the past 40 years to simulate the
mechanical behavior of bone. Although several validation studies have been performed on …

Abstract Image-Based Simulation (IBSim) is the process by which a digital representation of
a real geometry is generated from image data for the purpose of performing a simulation …

Finite element (FE) models have been widely used to investigate knee joint biomechanics.
Most of these models have been developed to study adult knees, neglecting pediatric …

Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Virtual representations of the knee joint can provide clinicians, scientists, and engineers the
tools to explore mechanical functions of the knee and its tissue structures in health and …