Centrifugal microfluidic platforms: advanced unit operations and applications

O Strohmeier, M Keller, F Schwemmer… - Chemical Society …, 2015 - pubs.rsc.org
Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic
companies either have products on the market or are currently evaluating centrifugal …

Polymerase chain reaction in microfluidic devices

CD Ahrberg, A Manz, BG Chung - Lab on a Chip, 2016 - pubs.rsc.org
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …

Recent progress of microfluidic reactors for biomedical applications

H Shi, K Nie, B Dong, M Long, H Xu, Z Liu - Chemical Engineering Journal, 2019 - Elsevier
Lab-on-a-chip has evolved into a powerful analytical tool that combines multiple disciplines
for biomedical research. The microfluidic reactor in lab-on-a-chip is regarded as a critical …

A review of biomedical centrifugal microfluidic platforms

M Tang, G Wang, SK Kong, HP Ho - Micromachines, 2016 - mdpi.com
Centrifugal microfluidic or lab-on-a-disc platforms have many advantages over other
microfluidic systems. These advantages include a minimal amount of instrumentation, the …

Rapid and fully automated bacterial pathogen detection on a centrifugal-microfluidic LabDisk using highly sensitive nested PCR with integrated sample preparation

G Czilwik, T Messinger, O Strohmeier, S Wadle… - Lab on a Chip, 2015 - pubs.rsc.org
Diagnosis of infectious diseases suffers from long turnaround times for gold standard culture-
based identification of bacterial pathogens, therefore impeding timely specific antimicrobial …

Micro total analysis systems: fundamental advances and applications

DEW Patabadige, S Jia, J Sibbitts, J Sadeghi… - Analytical …, 2016 - ACS Publications
It has been 14 years since the inaugural microfluidics review in Analytical Chemistry was
published. 1 The first papers describing these devices which are also commonly referred to …

Lab-on-a-CD: A fully integrated molecular diagnostic system

LX Kong, A Perebikovsky, J Moebius… - Journal of …, 2016 - journals.sagepub.com
The field of centrifugal microfluidics has experienced tremendous growth during the past 15
years, especially in applications such as lab-on-a-disc (LoD) diagnostics. The strength of …

Review on pneumatic operations in centrifugal microfluidics

JF Hess, S Zehnle, P Juelg, T Hutzenlaub, R Zengerle… - Lab on a Chip, 2019 - pubs.rsc.org
Centrifugal microfluidics allows for miniaturization, automation and parallelization of
laboratory workflows. The fact that centrifugal forces are always directed radially outwards …

Microfluidic-based nucleic acid amplification systems in microbiology

L Gorgannezhad, H Stratton, NT Nguyen - Micromachines, 2019 - mdpi.com
Rapid, sensitive, and selective bacterial detection is a hot topic, because the progress in this
research area has had a broad range of applications. Novel and innovative strategies for …

Automation of amplicon-based library preparation for next-generation sequencing by centrifugal microfluidics

JF Hess, M Kotrová, S Calabrese, N Darzentas… - Analytical …, 2020 - ACS Publications
Next-generation sequencing (NGS) has become a mainstream method in bioanalysis.
Improvements in sequencing and bioinformatics turned the complex and cumbersome …