Hypothalamic syndrome

HL Müller, M Tauber, EA Lawson, J Özyurt… - Nature reviews Disease …, 2022 - nature.com
Hypothalamic syndrome (HS) is a rare disorder caused by disease-related and/or treatment-
related injury to the hypothalamus, most commonly associated with rare, non-cancerous …

Pathophysiology and individualized treatment of hypothalamic obesity following craniopharyngioma and other suprasellar tumors: a systematic review

L van Iersel, KE Brokke, RAH Adan… - Endocrine …, 2019 - academic.oup.com
The development of hypothalamic obesity (HO) following craniopharyngioma (CP) and other
suprasellar tumors leads to reduced patient quality of life. No treatment algorithms are …

Craniopharyngioma and hypothalamic injury: latest insights into consequent eating disorders and obesity

HL Müller - Current Opinion in Endocrinology, Diabetes and …, 2016 - journals.lww.com
Craniopharyngioma and hypothalamic injury: latest insights i... : Current Opinion in
Endocrinology, Diabetes and Obesity Craniopharyngioma and hypothalamic injury: latest …

Diagnostic criteria for the hypothalamic syndrome in childhood

HM van Santen, J van Schaik… - European Journal of …, 2023 - academic.oup.com
Objective Hypothalamic syndrome (HS) in childhood is a rare condition. Its epidemiology is
not well known because incidence and prevalence are related to very rare underlying …

Implication of heterozygous variants in genes of the leptin–melanocortin pathway in severe obesity

S Courbage, C Poitou… - The Journal of …, 2021 - academic.oup.com
Context Unlike homozygous variants, the implication of heterozygous variants on the leptin–
melanocortin pathway in severe obesity has not been established. Objective To describe the …

Quality of life in craniopharyngioma: a systematic review

M Castle-Kirszbaum, MDY Shi, T Goldschlager - World Neurosurgery, 2022 - Elsevier
Background Craniopharyngiomas are morbid tumors that significantly reduce patients'
quality of life (QoL). The lifelong burden of endocrine, visual, hypothalamic, and limbic …

Clinical Significance of Plasma Leptin and Its Receptors mRNA Expression in Craniopharyngiomas: A Prospective Study

Y Xiao, W Wu, K Cai, L Jin, Y Jia, N Qiao, F Liu, S Ru… - Biomolecules, 2023 - mdpi.com
Craniopharyngioma (CP) is a benign tumor with a high rate of obesity and frequent
recurrence. Moreover, the role of leptin/leptin receptors axis in obesity and the prognosis of …

Risk-adapted, long-term management in childhood-onset craniopharyngioma

HL Müller - Pituitary, 2017 - Springer
Purpose This report is a review of findings on the diagnosis, treatment, clinical course, follow-
up, and prognosis of craniopharyngioma patients with special regard to clinical trials and …

Resting energy expenditure in children at risk of hypothalamic dysfunction

J Van Schaik, M Burghard, MH Lequin… - Endocrine …, 2022 - ec.bioscientifica.com
Objective Children with suprasellar brain damage are at risk of hypothalamic dysfunction
(HD). HD may lead to decreased resting energy expenditure (REE). Decreased REE …

Dextroamphetamine treatment in children with hypothalamic obesity

J van Schaik, MS Welling, CJ de Groot… - Frontiers in …, 2022 - frontiersin.org
Introduction Hypothalamic obesity (HO) in children has severe health consequences.
Lifestyle interventions are mostly insufficient and currently no drug treatment is approved for …