Osteosarcoma is the most common primary bone sarcoma and is often diagnosed in the 2nd–
3rd decades of life. Response to the aggressive and highly toxic neoadjuvant methotrexate …

Osteosarcoma (OS) is the most common type of primary bone tumor in children and
adolescents and has been associated with a high degree of malignancy, early metastasis …

Osteosarcoma is the most common malignant bone tumor, currently treated with pre-and
postoperative chemotherapy in association with the surgical removal of the tumor. About 15 …

Osteosarcoma (OSA) is a type of bone cancer that begins in the cells that form bones. OSA
is a rare mesenchymal bone neoplasm derived from mesenchymal stem cells. Genome …

Highlights•Although rare, bone cancers frequently cause death in the pediatric population.•
Osteosarcoma patient survival has plateaued over the last 20 years.•The large tumor …

Background The current study aims to determine cause-specific survival in patients with high-
grade osteosarcoma while reporting risk factors for decreased survival out to 10 years …

Gene therapy (GT) and photothermal therapy (PTT) have emerged as promising alternatives
to chemotherapy and radiotherapy for cancer treatment, offering noninvasiveness and …

Osteosarcoma is rare malignancy of childhood and adolescence, with high morbidity and
mortality despite accomplishment of diverse therapeutic modalities. Identification of the …

Objective: Triple-negative breast cancer (TNBC) involves higher rates of recurrence and
distant metastasis. The present study sought to characterize the risk factors for distant …

Objectives Osteosarcoma was the most popular primary malignant tumor in children and
adolescent, and the 5-year survival of osteosarcoma patients gained no substantial …