Vital internal organs display a left-right (LR) asymmetric arrangement that is established
during embryonic development. Disruption of this LR asymmetry—or laterality—can result in …

Transgenesis is an essential technique for any genetic model. Tol2-based transgenesis
paired with Gateway-compatible vector collections has transformed zebrafish transgenesis …

Piperlongumine (PL) and piperine (PP) are alkaloids presented in long pepper (Piper
longum), and they exhibit various biological activities, especially anti-cancer properties. With …

Developmental studies have shown that the evolutionarily conserved Wnt Planar Cell
Polarity (PCP) pathway is essential for the development of a diverse range of tissues and …

The establishment of the left-right axis is crucial for the placement, morphogenesis and
function of internal organs. Left-right specification is proposed to be dependent on cilia …

Zebrafish (Danio rerio) is a well-established model organism for studying melanocyte
biology due to its remarkable similarity to humans. The Wnt signalling pathway is a …

Dextrocardia is a rare congenital malformation in humans in which most of the heart mass is
positioned in the right hemithorax rather than on the left. The heart itself may be normal and …

Asymmetric vertebrate heart development is driven by an intricate sequence of
morphogenetic cell movements, the coordination of which requires precise interpretation of …

The mechanisms underlying the establishment of asymmetric structures during development
remain elusive. The wing of Drosophila is asymmetric along the Anterior-Posterior (AP) axis …

Melanocytes, which are derived from the multipotent neural crest, are found in the skin, eyes,
and other diverse anatomical locations of the vertebrates. The main aspects of melanocyte …