Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …

The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause for dementia. There are many hypotheses about AD, including abnormal …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and …

The central nervous system (CNS) and the immune system are both intricate and highly
organized systems that regulate the entire body, with both sharing certain common features …

The decline of cognitive function has emerged as one of the greatest health threats of old
age. Age-related cognitive decline is caused by an impacted neuronal circuitry, yet the …

Synaptic dysfunction in CNS disorders is the outcome of perturbations in physiological
synapse structure and function, and can be either the cause or the consequence in specific …

Down syndrome (DS) is a neurological disorder with multiple immune-related symptoms;
however, crosstalk between the CNS and peripheral immune system remains unexplored …

Schizophrenia is a debilitating disease that presents with both positive and negative
symptoms affecting cognition and emotions. Extensive studies have analyzed the different …