Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Faced with the need to find new anti-inflammatory agents, great effort has been expended
on the development of drugs for the treatment of inflammation. This disorder reduces the …

Musculoskeletal diseases affect up to 20% of adults worldwide. The gut microbiome has
been implicated in inflammatory conditions, but large-scale metagenomic evaluations have …

Colon cancer is the major health hazard related with high mortality and it is a pathological
consequence of persistent oxidative stress and inflammation. Farnesol, an isoprenoid …

Mevalonate kinase deficiency (MKD) is a recessively inherited autoinflammatory disorder
with a spectrum of manifestations, including the well-defined clinical phenotypes of …

Isoprenoids are the output of the polymerization of five-carbon, branched isoprenic chains
derived from isopentenyl pyrophosphate (IPP) and its isomer, dimethylallyl pyrophosphate …

The objective of the present study was to perform a systematic review (SR) composed of
preclinical and clinical studies which investigated the toxicological and pharmacologic …

Mevalonate kinase deficiency or hyper-IgD syndrome is a hereditary autoinflammatory
syndrome caused by mutations in the mevalonate kinase gene. In this review, we will …

Isoprenoids play widely differing roles in various physiological processes in animals and
plants. Geranylgeraniol (GGOH) is an isoprenoid found in plants, and is an important …

ABSTRACT Introduction: Farnesol (C15H26O) is a sesquiterpene alcohol found in essential
oils. This substance is reported to have different pharmacological activities such as …