[HTML][HTML] The CRISPR tool kit for genome editing and beyond

M Adli - Nature communications, 2018 - nature.com
CRISPR is becoming an indispensable tool in biological research. Once known as the
bacterial immune system against invading viruses, the programmable capacity of the Cas9 …

Insights into the mechanism of CRISPR/Cas9-based genome editing from molecular dynamics simulations

S Bhattacharya, P Satpati - ACS omega, 2022 - ACS Publications
The CRISPR/Cas9 system is a popular genome-editing tool with immense therapeutic
potential. It is a simple two-component system (Cas9 protein and RNA) that recognizes the …

[HTML][HTML] All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo

R Ibraheim, CQ Song, A Mir, N Amrani, W Xue… - Genome biology, 2018 - Springer
Background Clustered, regularly interspaced, short palindromic repeats (CRISPR) and
CRISPR-associated proteins (Cas) have recently opened a new avenue for gene therapy …

Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

D Agudelo, S Carter, M Velimirovic, A Duringer… - Genome …, 2020 - genome.cshlp.org
Targeting definite genomic locations using CRISPR-Cas systems requires a set of enzymes
with unique protospacer adjacent motif (PAM) compatibilities. To expand this repertoire, we …

[HTML][HTML] An overview of the CRISPR-Based genomic-and epigenome-editing system: function, applications, and challenges

SB Qomi, A Asghari, M Mojarrad - Advanced Biomedical Research, 2019 - journals.lww.com
Developing a new strategy for an efficient targeted genome editing has always been a great
perspective in biology. Although different approaches have been suggested in the last three …

Reprogramming Adeno-Associated Virus Tropism Via Displayed Peptides Tiling Receptor-Ligands

A Portell, KM Ford, A Suhardjo, J Rainaldi, MN Bublik… - bioRxiv, 2022 - biorxiv.org
Adeno-associated viruses (AAVs) are common gene therapy vectors, however, their
effectiveness is hindered by poor target tissue transduction and off-target delivery …

Basic and clinical application of adeno-associated virus–mediated genome editing

X He, H Xie, X Liu, F Gu - Human gene therapy, 2019 - liebertpub.com
Traditional gene therapy (gene replacement) has made a breakthrough in treating inherited
diseases. Adeno-associated virus (AAV) has emerged as a highly promising vector with …

[HTML][HTML] Biología sintética en la obtención de compuestos de interés para la industria alimentaria

MP Ortuño-Fajardo, JR Chacón-Halabi… - Revista Tecnología en …, 2021 - scielo.sa.cr
La ingeniería de rutas metabólicas, por medio de la biología sintética, se ha convertido en
una herramienta de suma importancia para la industria alimentaria, debido a que se busca …

[HTML][HTML] Synthetic biology as a tool used to obtain compounds of interest in the food industry

MP Ortuño-Fajardo, JR Chacón-Halabi… - Revista Tecnología en …, 2021 - scielo.sa.cr
La ingeniería de rutas metabólicas, por medio de la biología sintética, se ha convertido en
una herramienta de suma importancia para la industria alimentaria, debido a que se busca …

Biología sintética en la ingenierización de rutas metabólicas de microorganismos para la obtención de compuestos de interés para la industria alimentaria

MPO Fajardo, JRC Halabi, MPF Espinoza… - Tecnología en …, 2021 - dialnet.unirioja.es
La ingeniería de rutas metabólicas, por medio de la biología sintética, se ha convertido en
una herramienta de suma importancia para la industria alimentaria, debido a que se busca …